N-Cyclohexyl-4-((2-oxo-1,2-dihydroquinolin-6-yl)oxy)butanamide

Base Information

Chemical Name:N-Cyclohexyl-4-((2-oxo-1,2-dihydroquinolin-6-yl)oxy)butanamide
CAS No.:69592-36-5
Molecular Formula:C₁₉H₂₄N₂O₃
Molecular Weight:328.411
Hs Code.:
DSSTox Substance ID:DTXSID00518736
Wikidata:Q82381541

Synonyms:69592-36-5;N-Cyclohexyl-4-((2-oxo-1,2-dihydroquinolin-6-yl)oxy)butanamide;N-Cyclohexyl-4-[(2-oxo-1,2-dihydroquinolin-6-yl)oxy]butanamide;SCHEMBL11324806;DTXSID00518736

Suppliers and Price of N-Cyclohexyl-4-((2-oxo-1,2-dihydroquinolin-6-yl)oxy)butanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N-Cyclohexyl-4-((2-oxo-1,2-dihydroquinolin-6-yl)oxy)butanamide

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:328.17869263
Heavy Atom Count:24
Complexity:471

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCC(CC1)NC(=O)CCCOC2=CC3=C(C=C2)NC(=O)C=C3

Technology Process of N-Cyclohexyl-4-((2-oxo-1,2-dihydroquinolin-6-yl)oxy)butanamide

There total 4 articles about N-Cyclohexyl-4-((2-oxo-1,2-dihydroquinolin-6-yl)oxy)butanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 19315-93-6
6-hydroxy-1H-quinolin-2-one

: 69592-36-5
6-[3-(N-cyclohexylaminocarbonyl)propoxy]carbostyril

Guidance literature:: Multi-step reaction with 3 steps

1: 74 percent / 1,8-diazabicyclo<5,4,0>undec-7-ene (DBU) / propan-2-ol / 4 h / Heating

2: 95 percent / 20percent HCl / 2 h / 85 - 90 °C

3: 1.) isobutyl chloroformate, 1,8-diazabicyclo<5,4,0>undec-7-ene (DBU) / 1.) CHCl₃, r.t., 1 h, 2.) CHCl₃, r.t., 3 h

With hydrogenchloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; isobutyl chloroformate; In isopropyl alcohol;
DOI:10.1248/cpb.31.852

Reference yield:

: 87364-41-8
methyl 4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyrate

: 69592-36-5
6-[3-(N-cyclohexylaminocarbonyl)propoxy]carbostyril

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / 20percent HCl / 2 h / 85 - 90 °C

2: 1.) isobutyl chloroformate, 1,8-diazabicyclo<5,4,0>undec-7-ene (DBU) / 1.) CHCl₃, r.t., 1 h, 2.) CHCl₃, r.t., 3 h

With hydrogenchloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; isobutyl chloroformate;
DOI:10.1248/cpb.31.852

Reference yield:

: 58899-33-5
4-(2-oxo-1,2-dihydro-quinolin-6-yloxy)-butyric acid

: 108-91-8,157973-60-9
cyclohexylamine

: 69592-36-5
6-[3-(N-cyclohexylaminocarbonyl)propoxy]carbostyril

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; isobutyl chloroformate; Yield given. Multistep reaction; 1.) CHCl₃, r.t., 1 h, 2.) CHCl₃, r.t., 3 h;
DOI:10.1248/cpb.31.852