4-[(5-Chloro-2-nitrophenyl)methanesulfonyl]morpholine

Base Information

Chemical Name:4-[(5-Chloro-2-nitrophenyl)methanesulfonyl]morpholine
CAS No.:69709-37-1
Molecular Formula:C11H13ClN2O5S
Molecular Weight:320.754
Hs Code.:
DSSTox Substance ID:DTXSID00498645
Wikidata:Q82348838

Synonyms:69709-37-1;4-[(5-Chloro-2-nitrophenyl)methanesulfonyl]morpholine;DTXSID00498645

Suppliers and Price of 4-[(5-Chloro-2-nitrophenyl)methanesulfonyl]morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-[(5-Chloro-2-nitrophenyl)methanesulfonyl]morpholine

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:320.0233704
Heavy Atom Count:20
Complexity:441

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1S(=O)(=O)CC2=C(C=CC(=C2)Cl)[N+](=O)[O-]

Technology Process of 4-[(5-Chloro-2-nitrophenyl)methanesulfonyl]morpholine

There total 1 articles about 4-[(5-Chloro-2-nitrophenyl)methanesulfonyl]morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 100-00-5
4-chlorobenzonitrile

: 39542-27-3
4-chloromethanesulfonyl-morpholine

: 69709-37-1
5-chloro-2-nitrobenzyl 4-morpholinyl sulfone

Guidance literature:: With potassium hydroxide; In dimethyl sulfoxide; for 1h; Ambient temperature;
DOI:10.1021/jo00183a003

Reference yield: 94.0%

: 69709-37-1
5-chloro-2-nitrobenzyl 4-morpholinyl sulfone

: 107266-90-0
4-Chloro-2-(morpholine-4-sulfonylmethyl)-phenylamine

Guidance literature:: With hydrogenchloride; tin; In methanol; at 30 - 40 ℃;
DOI:10.1055/s-1986-33421

Reference yield:

: 69709-37-1
5-chloro-2-nitrobenzyl 4-morpholinyl sulfone

: 107266-97-7
N-[4-Chloro-2-(morpholine-4-sulfonylmethyl)-phenyl]-acetimidic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / Sn, conc. aq. HCl / methanol / 30 - 40 °C

2: 97 percent / p-toluenesulfonic acid / 2 h / Heating

With hydrogenchloride; tin; toluene-4-sulfonic acid; In methanol;
DOI:10.1055/s-1986-33421