2,5-Diphenyl-6H-1,3,4-oxadiazin-6-one

Base Information

• Chemical Name: 2,5-Diphenyl-6H-1,3,4-oxadiazin-6-one
• CAS No.: 63617-45-8
• Molecular Formula: C15H10N2O2
• Molecular Weight: 250.257
• Mol file: 63617-45-8.mol

Synonyms:[1,2,4]Triazolo[1,5-c]quinazoline,2,5-diphenyl;2,5-diphenyl<1,2,4>triazolo<1,5-c>quinazoline;2,5-diphenyl-[1,3,4]oxadiazin-6-one;

Chemical Property of 2,5-Diphenyl-6H-1,3,4-oxadiazin-6-one

Chemical Property:

• Vapor Pressure: 8.55E-06mmHg at 25°C
• Boiling Point: 374.1°Cat760mmHg
• Flash Point: 169.6°C
• PSA: 55.99000
• Density: 1.24g/cm³
• LogP: 2.76380

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,5-Diphenyl-6H-1,3,4-oxadiazin-6-one

There total 5 articles about 2,5-Diphenyl-6H-1,3,4-oxadiazin-6-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

(Z)-α-(benzoylhydrazono)phenylacetic acid (88062-46-8) → 2,5-diphenyl-6H-1,3,4-oxadiazin-6-one (63617-45-8)

Guidance literature:

With dicyclohexyl-carbodiimide; In tetrahydrofuran; for 16h; Ambient temperature;

Reference yield:

benzoylformic acid (N-benzoyl)hydrazone (5199-89-3) → 2,5-diphenyl-6H-1,3,4-oxadiazin-6-one (63617-45-8)

Guidance literature:

With dicyclohexyl-carbodiimide; In tetrahydrofuran;

DOI:10.1055/s-1977-24339

Reference yield:

benzoic acid hydrazide (613-94-5) → 2,5-diphenyl-6H-1,3,4-oxadiazin-6-one (63617-45-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 63 percent / sodium hydrogen carbonate / aq. ethanol / 16 h / Ambient temperature

2: 65 percent / dicyclohexylcarbodiimide / tetrahydrofuran / 16 h / Ambient temperature

With sodium hydrogencarbonate; dicyclohexyl-carbodiimide; In tetrahydrofuran; ethanol;

upstream raw materials:

benzoylformic acid (N-benzoyl)hydrazone

(Z)-α-(benzoylhydrazono)phenylacetic acid

benzoic acid hydrazide

Benzoylformic acid

Downstream raw materials:

benzaldehyde

Phenyl-{[1-phenyl-1-(2-pyrrolidin-1-yl-cyclopent-1-enyl)-meth-(E)-ylidene]-hydrazono}-acetic acid

Lithium; [((E)-2-cyano-1,2-diphenyl-vinyl)-hydrazono]-phenyl-acetate

3,exo-6-Diphenyl-4-oxa-exo-tricyclo<6.2.1.0^2,7>undeca-2,9-dien-5-on