Ethyl beta-hydroxy-2-methylbenzenepropanoate

Base Information

Chemical Name:Ethyl beta-hydroxy-2-methylbenzenepropanoate
CAS No.:70200-17-8
Molecular Formula:C12H16O3
Molecular Weight:208.257
Hs Code.:
DSSTox Substance ID:DTXSID901270392

Synonyms:70200-17-8;SCHEMBL10249906;DTXSID901270392;AKOS011681475;Ethyl beta-hydroxy-2-methylbenzenepropanoate

Suppliers and Price of Ethyl beta-hydroxy-2-methylbenzenepropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Ethyl beta-hydroxy-2-methylbenzenepropanoate

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:208.109944368
Heavy Atom Count:15
Complexity:203

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC(C1=CC=CC=C1C)O

Technology Process of Ethyl beta-hydroxy-2-methylbenzenepropanoate

There total 4 articles about Ethyl beta-hydroxy-2-methylbenzenepropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 4071-88-9
trimethylsilanyl-acetic acid ethyl ester

: 529-20-4
2-methylphenyl aldehyde

: 70200-17-8,820976-83-8
ethyl 3-hydroxy-3-(2-methylphenyl)propanoate

Guidance literature:: trimethylsilanyl-acetic acid ethyl ester; 2-methylphenyl aldehyde; With 1,3-bis-(2,6-diisopropylphenyl)-imidazol-2-ylidene; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 24h; Inert atmosphere; Green chemistry;

With hydrogenchloride; In water; N,N-dimethyl-formamide; for 0.5h; Inert atmosphere; Green chemistry;
DOI:10.1016/j.tet.2012.11.015

Reference yield:

: 51725-82-7
ethyl (2-methylbenzoyl)acetate

: 70200-17-8,820976-83-8
ethyl 3-hydroxy-3-(2-methylphenyl)propanoate

Guidance literature:: With sodium tetrahydroborate;
DOI:10.1016/j.tet.2006.03.045

Reference yield:

: 141-78-6
ethyl acetate

: 529-20-4
2-methylphenyl aldehyde

: 70200-17-8,820976-83-8
ethyl 3-hydroxy-3-(2-methylphenyl)propanoate

Guidance literature:: ethyl acetate; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 - 0 ℃; for 0.5h; Inert atmosphere;

2-methylphenyl aldehyde; In tetrahydrofuran; hexane; at -78 ℃; Inert atmosphere;
DOI:10.1021/acs.orglett.9b00053