Technology Process of 2-Pentenoic acid, 3-methyl-5-phenyl-, ethyl ester, (2Z)-
There total 9 articles about 2-Pentenoic acid, 3-methyl-5-phenyl-, ethyl ester, (2Z)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
diethoxyphosphoryl-acetic acid ethyl ester;
With
sodium hydride;
In
tetrahydrofuran; mineral oil;
at 0 - 20 ℃;
for 1h;
Inert atmosphere;
4-Phenyl-2-butanone;
In
tetrahydrofuran; mineral oil;
at 20 ℃;
- Guidance literature:
-
diethoxyphosphoryl-acetic acid ethyl ester;
With
1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride;
In
acetonitrile;
at 23 ℃;
for 0.25h;
Inert atmosphere;
4-Phenyl-2-butanone;
In
acetonitrile;
at 0 - 23 ℃;
for 0.5h;
Inert atmosphere;
DOI:10.1021/jacs.9b09373
- Guidance literature:
-
trimethylaluminum;
With
zirconocene dichloride;
In
dichloromethane; water;
at -22 ℃;
for 0.333333h;
Inert atmosphere;
Sealed tube;
4-Phenyl-1-butyne;
In
dichloromethane; water;
Inert atmosphere;
Sealed tube;
chloroformic acid ethyl ester;
In
dichloromethane; water;
at -22 - 20 ℃;
for 2h;
Inert atmosphere;
Sealed tube;
DOI:10.1016/j.chempr.2018.04.008
