Ethyl chloroformate

Base Information Edit

Chemical Name:Ethyl chloroformate
CAS No.:541-41-3
Deprecated CAS:52803-29-9,503842-49-7,503842-49-7
Molecular Formula:C3H5ClO2
Molecular Weight:108.525
Hs Code.:2915.13
European Community (EC) Number:208-778-5
ICSC Number:1025
UN Number:1182
UNII:09601EZP9R
DSSTox Substance ID:DTXSID1027186
Nikkaji Number:J53.980E
Wikipedia:Ethyl_chloroformate
Wikidata:Q288339
ChEMBL ID:CHEMBL3183406
Mol file:541-41-3.mol

Synonyms:ethyl chloroformate;ethyl chloroformate, 14C-labeled;ethylchloroformate

Suppliers and Price of Ethyl chloroformate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl chloroformate
5g
$ 50.00

Sigma-Aldrich
Ethyl chloroformate 97%
100g
$ 30.50

Sigma-Aldrich
Ethyl chloroformate 97%
5g
$ 21.60

Sigma-Aldrich
Ethyl chloroformate 97%
500g
$ 130.00

Sigma-Aldrich
Ethyl chloroformate 97%
2kg
$ 335.00

Medical Isotopes, Inc.
Ethyl chloroformate
50 g
$ 650.00

Medical Isotopes, Inc.
Ethyl chloroformate
100 g
$ 775.00

Alfa Aesar
Ethyl chloroformate 97%
500g
$ 289.00

Alfa Aesar
Ethyl chloroformate 97%
100g
$ 74.40

Alfa Aesar
Ethyl chloroformate 97%
5g
$ 19.40

Total 1 raw suppliers

Chemical Property of Ethyl chloroformate Edit

Chemical Property:

Appearance/Colour:Colorless to yellow liquid
Vapor Pressure:3.42 psi ( 20 °C)
Melting Point:-81 °C
Refractive Index:n20/D 1.395(lit.)
Boiling Point:95 °C at 760 mmHg
Flash Point:18.8 °C
PSA：26.30000
Density:1.167 g/cm³
LogP:1.38170
Storage Temp.:2-8°C
Sensitive.:Moisture Sensitive
Solubility.:Chloroform (Soluble), Ethyl Acetate (Slightly)
Water Solubility.:decomposes
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:107.9978071
Heavy Atom Count:6
Complexity:52.8
Transport DOT Label:Poison Inhalation Hazard Flammable Liquid Corrosive

Purity/Quality:

97% ^*data from raw suppliers

Ethyl chloroformate ^*data from reagent suppliers

Safty Information:

Pictogram(s): F, T+
Hazard Codes:F,T+,N
Statements: 11-22-26-34-50
Safety Statements: 9-16-26-28-33-36/37/39-45-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Toxic Gases & Vapors -> Acid Halides
Canonical SMILES:CCOC(=O)Cl
Recent ClinicalTrials:Combination Chemotherapy and Cetuximab in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer
Inhalation Risk:A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20 °C.
Effects of Short Term Exposure:Lachrymation. The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of the vapour may cause lung oedema.
Uses Ethyl chloroformate (chloroformic acid ethyl ester) is used as a solvent in the photographic industry, and as a chemical intermediate in the production of various carbamates, and used in synthesis of dyes, drugs, veterinary medicines, herbicides, and insecticides. It is also used in the production of flotation agents for ores, as a stabilizer for PVC, and in the production of modified penicillins and heterocyclic compounds (Gerhartz, 1985). Cathyl Chloride is used in the preparation of new inhibitors for β-homocysteine S-methyltransferase. Also used in the synthesis of a hexosaminidase inhibitor.

Technology Process of Ethyl chloroformate

There total 31 articles about Ethyl chloroformate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%