3-(Quinolin-3-yl)prop-2-yn-1-ol

Base Information

Chemical Name:3-(Quinolin-3-yl)prop-2-yn-1-ol
CAS No.:70437-05-7
Molecular Formula:C12H9NO
Molecular Weight:183.21
Hs Code.:
DSSTox Substance ID:DTXSID10349497
Nikkaji Number:J2.356.541B
Wikidata:Q82124788
ChEMBL ID:CHEMBL1587768
Mol file:70437-05-7.mol

Synonyms:70437-05-7;3-(Quinolin-3-yl)prop-2-yn-1-ol;3-quinolin-3-ylprop-2-yn-1-ol;3-(3-quinolinyl)-2-propyn-1-ol;MLS000029796;3-Quinolin-3-yl-prop-2-yn-1-ol;Oprea1_286776;SCHEMBL372200;CHEMBL1587768;DTXSID10349497;3-(3-quinoyl)-2-propyn-1-ol;BATAIOGYFWEXQV-UHFFFAOYSA-N;3-(3-quinolyl)-2-propyn-1-ol;HMS1674L13;HMS2178C07;MFCD02737713;STL513415;AKOS000582962;SMR000012067;AN-919/40843343;F9994-3237

Suppliers and Price of 3-(Quinolin-3-yl)prop-2-yn-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 3-(Quinolin-3-yl)prop-2-yn-1-ol

Chemical Property:

PSA：33.12000
LogP:1.57860
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:183.068413911
Heavy Atom Count:14
Complexity:250

Purity/Quality:: NLT 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=C(C=N2)C#CCO

Technology Process of 3-(Quinolin-3-yl)prop-2-yn-1-ol

There total 2 articles about 3-(Quinolin-3-yl)prop-2-yn-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.3%

: 70437-05-7
3-(3-quinolinyl)-2-propyn-1-ol

Guidance literature:

Reference yield: 81.0%

: 5332-24-1
3-bromoquinoline

: 107-19-7
propargyl alcohol

: 70437-05-7
3-(3-quinolinyl)-2-propyn-1-ol

Guidance literature:: With caesium carbonate; bis(η3-allyl-μ-chloropalladium(II)); In tetrahydrofuran; toluene; at 20 ℃; for 16h;
DOI:10.1039/b516398f

Reference yield: 74.0%

: 70437-05-7
3-(3-quinolinyl)-2-propyn-1-ol

: 173019-85-7
3-bromo-1-(4-methoxyphenyl)propyne

: 3-(3-(3-(4-methoxyphenyl)prop-2-ynyloxy)prop-1-ynyl)quinoline

Guidance literature:: 3-(3-quinolinyl)-2-propyn-1-ol; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 0.5h; Cooling with ice; Inert atmosphere;

3-bromo-1-(4-methoxyphenyl)propyne; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1016/j.tet.2019.02.020