(S)-2-(1-Hydroxy-3-phenylpropan-2-YL)isoindoline-1,3-dione

Base Information

Chemical Name:(S)-2-(1-Hydroxy-3-phenylpropan-2-YL)isoindoline-1,3-dione
CAS No.:70451-01-3
Molecular Formula:C17H15NO3
Molecular Weight:281.311
Hs Code.:
DSSTox Substance ID:DTXSID40462406
Nikkaji Number:J1.493.271B

Synonyms:(S)-2-(1-HYDROXY-3-PHENYLPROPAN-2-YL)ISOINDOLINE-1,3-DIONE;70451-01-3;(2S)-2-Phthalimido-3-phenyl-propanol;2-[(2S)-1-hydroxy-3-phenylpropan-2-yl]isoindole-1,3-dione;SCHEMBL3444977;DTXSID40462406;2-[(2S)-1-hydroxy-3-phenylpropan-2-yl]-2,3-dihydro-1H-isoindole-1,3-dione;WUQQWFQBZMAJLS-ZDUSSCGKSA-N;2-[(1S)-1-benzyl-2-hydroxyethyl]-1H-isoindole-1,3(2H)-dione

Suppliers and Price of (S)-2-(1-Hydroxy-3-phenylpropan-2-YL)isoindoline-1,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (S)-2-(1-Hydroxy-3-phenylpropan-2-YL)isoindoline-1,3-dione

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:281.10519334
Heavy Atom Count:21
Complexity:379

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(CO)N2C(=O)C3=CC=CC=C3C2=O
Isomeric SMILES:C1=CC=C(C=C1)C[C@@H](CO)N2C(=O)C3=CC=CC=C3C2=O

Technology Process of (S)-2-(1-Hydroxy-3-phenylpropan-2-YL)isoindoline-1,3-dione

There total 8 articles about (S)-2-(1-Hydroxy-3-phenylpropan-2-YL)isoindoline-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 85-44-9
phthalic anhydride

: 3182-95-4
L-Phenylalaninol

: 70451-01-3
(-)-(S)-2-(1-benzyl-2-hydroxyethyl)-1H-isoindole-1,3(2H)-dione

Guidance literature:: With triethylamine; In toluene; at 145 ℃; for 41h;
DOI:10.1002/anie.200604557

Reference yield: 100.0%

: (S)-(-)-2-amino-3-phenyl-1-propanol hydrochloride salt

: 438470-19-0
methyl 2-(N-succinimidyloxycarbonyl)benzoate

: 70451-01-3
(-)-(S)-2-(1-benzyl-2-hydroxyethyl)-1H-isoindole-1,3(2H)-dione

Guidance literature:: With potassium carbonate; In acetonitrile; at 20 ℃; for 6h;
DOI:10.1021/jo016347h

Reference yield:

: 85-44-9
phthalic anhydride

: 63-91-2,25191-15-5,658-69-5,67675-33-6
L-phenylalanine

: 70451-01-3
(-)-(S)-2-(1-benzyl-2-hydroxyethyl)-1H-isoindole-1,3(2H)-dione

Guidance literature:: L-phenylalanine; With sodium tetrahydroborate; In tetrahydrofuran; at 0 ℃; for 16h; Inert atmosphere; Reflux;

phthalic anhydride; With triethylamine; In toluene; for 6h; Dean-Stark; Reflux;
DOI:10.1021/acs.orglett.8b01023