438470-19-0Relevant articles and documents
Palladium-Catalyzed Carbonylation of (Hetero)Aryl, Alkenyl and Allyl Halides by Means of N-Hydroxysuccinimidyl Formate as CO Surrogate
Barré, Ana?s,T?nta?, Mihaela-Liliana,Alix, Florent,Gembus, Vincent,Papamica?l, Cyril,Levacher, Vincent
, p. 6537 - 6544 (2015/10/05)
An efficient Pd-catalyzed carbonylation protocol is described for the coupling of a large panel of aryl, heteroaryl, benzyl, vinyl and allyl halides 2 with the unusual N-hydroxysuccinimidyl (NHS) formate 1 as a CO surrogate to afford the corresponding valuable NHS esters 3. High conversion to the coupling products was achieved with up to 98% yield by means of Pd(OAc)2/Xantphos catalyst system.
Sialyltransferase inhibitors: Consideration of molecular shape and charge/hydrophobic interactions
Kumar, Rishi,Nasi, Ravindranath,Bhasin, Milan,Khieu, Nam Huan,Hsieh, Margaret,Gilbert, Michel,Jarrell, Harold,Zou, Wei,Jennings, Harold J.
, p. 45 - 55 (2013/10/21)
In order to evaluate the importance of molecular shape of inhibitor molecules and the charge/H-bond and hydrophobic interactions, we synthesized three types of molecules and tested them against a sialyltransferase. The first type of compounds were designe
Stereoselective synthesis of brevianamide e
Zhao, Liang,May, Jonathan P.,Huang, Jack,Perrin, David M.
supporting information; experimental part, p. 90 - 93 (2012/02/15)
The hydroxypyrroloindolenine (Hpi) motif forms the fundamental core of the pentacyclic natural product, brevianamide E, the concise stereoselective synthesis of which, via oxidative cyclization, is described.
Artificial molecular clamp: A novel device for synthetic polymerases
Takashima, Yoshinori,Osaki, Motofumi,Ishimaru, Yoshihiro,Yamaguchi, Hiroyasu,Harada, Akira
supporting information; experimental part, p. 7524 - 7528 (2011/10/04)
Synthetic polymerases composed of a cyclodextrin (CD) dimer yield high-molecular-weight polymers of cyclic esters without using solvents and co-catalysts. One CD moiety is attached to the active site of a supramolecular catalyst and propagates the polymerization by serving as artificial molecular clamp (see picture). The other CD moiety initiates the ring-opening polymerization. Copyright
Methyl 2-((succinimidooxy)carbonyl)benzoate (MSB): a new, efficient reagent for N-phthaloylation of amino acid and peptide derivatives.
Casimir, J Richard,Guichard, Gilles,Briand, Jean-Paul
, p. 3764 - 3768 (2007/10/03)
A new, efficient, and readily available reagent, methyl 2-((succinimidooxy)carbonyl)benzoate (MSB), for N-phthaloylation of amino acids and amino acid derivatives is described. The phthaloylation procedure is simple and racemization-free and gives excellent results with alpha-amino acids, alpha-amino alcohols, dipeptides, alpha-amino carboxamides, and alpha-amino esters.
