5-(Aminosulphonyl)-N-(2,5-dichloropentyl)-2-methoxybenzamide

Base Information

Chemical Name:5-(Aminosulphonyl)-N-(2,5-dichloropentyl)-2-methoxybenzamide
CAS No.:67833-50-5
Molecular Formula:C13H18Cl2N2O4S
Molecular Weight:369.269
Hs Code.:
European Community (EC) Number:267-298-4
DSSTox Substance ID:DTXSID10987176
Nikkaji Number:J29.490J

Synonyms:EINECS 267-298-4;67833-50-5;5-(Aminosulphonyl)-N-(2,5-dichloropentyl)-2-methoxybenzamide;C13H18Cl2N2O4S;N-(2,5-dichloropentyl)-2-methoxy-5-sulfamoylbenzamide;SCHEMBL10723373;DTXSID10987176;QTWZISKLRIHFNO-UHFFFAOYSA-N;N-(2,5-dichloropentyl)-2-methoxy-5-sulphamoyl-benzamide;N-(2,5-Dichloropentyl)-2-methoxy-5-sulfamoylbenzene-1-carboximidic acid

Suppliers and Price of 5-(Aminosulphonyl)-N-(2,5-dichloropentyl)-2-methoxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of 5-(Aminosulphonyl)-N-(2,5-dichloropentyl)-2-methoxybenzamide

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：110.36000
Density:1.358g/cm³
LogP:4.05470
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:368.0364336
Heavy Atom Count:22
Complexity:455

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)S(=O)(=O)N)C(=O)NCC(CCCCl)Cl

Technology Process of 5-(Aminosulphonyl)-N-(2,5-dichloropentyl)-2-methoxybenzamide

There total 4 articles about 5-(Aminosulphonyl)-N-(2,5-dichloropentyl)-2-methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51904-91-7
5-chlorosulfonyl-2-anisic acid

: 67833-50-5
N-(2,5-dichloropentyl)-2-methoxy-5-sulfamoylbenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: 94.6 percent / NH₃ / tetrahydrofuran / 0.5 h / Ambient temperature

2: 1.) ClCO₂Et, Et₃N, 2.) Et₃N / 1.) acetone, 0 deg C, 0.5 h, 2.) 0 deg C, 0.5 h then r.t., 2.5 h

With ammonia; chloroformic acid ethyl ester; triethylamine; In tetrahydrofuran;
DOI:10.1021/jm00124a024

Reference yield:

: 579-75-9
2-Methoxybenzoic acid

: 67833-50-5
N-(2,5-dichloropentyl)-2-methoxy-5-sulfamoylbenzamide

Guidance literature:: Multi-step reaction with 3 steps

1: 84.9 percent / chlorosulfuric acid / 0.67 h / 60 - 70 °C

2: 94.6 percent / NH₃ / tetrahydrofuran / 0.5 h / Ambient temperature

3: 1.) ClCO₂Et, Et₃N, 2.) Et₃N / 1.) acetone, 0 deg C, 0.5 h, 2.) 0 deg C, 0.5 h then r.t., 2.5 h

With chlorosulphuric acid; ammonia; chloroformic acid ethyl ester; triethylamine; In tetrahydrofuran;
DOI:10.1021/jm00124a024

Reference yield:

: 22117-85-7
2-methoxy-5-sulfamoylbenzoic acid

: 62922-45-6
2,5-dichloropentylamine hydrochloride

: 67833-50-5
N-(2,5-dichloropentyl)-2-methoxy-5-sulfamoylbenzamide

Guidance literature:: With chloroformic acid ethyl ester; triethylamine; Yield given. Multistep reaction; 1.) acetone, 0 deg C, 0.5 h, 2.) 0 deg C, 0.5 h then r.t., 2.5 h;
DOI:10.1021/jm00124a024