3-Chloro-2-(4-methylphenyl)-2H-indazole

Base Information

Chemical Name:3-Chloro-2-(4-methylphenyl)-2H-indazole
CAS No.:70704-41-5
Molecular Formula:C14H11ClN2
Molecular Weight:242.708
Hs Code.:
DSSTox Substance ID:DTXSID10500349
Wikidata:Q82351873

Synonyms:3-Chloro-2-(p-tolyl)-2H-indazole;70704-41-5;3-Chloro-2-(4-methylphenyl)-2H-indazole;DTXSID10500349

Suppliers and Price of 3-Chloro-2-(4-methylphenyl)-2H-indazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 3-Chloro-2-(4-methylphenyl)-2H-indazole

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:242.0610761
Heavy Atom Count:17
Complexity:263

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)N2C(=C3C=CC=CC3=N2)Cl

Technology Process of 3-Chloro-2-(4-methylphenyl)-2H-indazole

There total 3 articles about 3-Chloro-2-(4-methylphenyl)-2H-indazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 4-methylphenyl(mesityl)iodonium trifluoromethanesulfonate

: 29110-74-5
3-chloroindazole

: 70704-41-5
3-chloro-2-(p-tolyl)-2H-indazole

Guidance literature:: With copper(l) chloride; In dichloromethane; at 80 ℃; for 12h; regioselective reaction; Inert atmosphere; Sealed tube;
DOI:10.1039/c8ob00128f

Reference yield:

: 624-31-7
4-tolyl iodide

: 70704-41-5
3-chloro-2-(p-tolyl)-2H-indazole

Guidance literature:: Multi-step reaction with 2 steps

1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 20 °C / Inert atmosphere

2: copper(l) chloride / dichloromethane / 12 h / 80 °C / Inert atmosphere; Sealed tube

With 3-chloro-benzenecarboperoxoic acid; copper(l) chloride; In dichloromethane;
DOI:10.1039/c8ob00128f