Methyl 2-isocyano-2-methylpropanoate

Base Information

Chemical Name:Methyl 2-isocyano-2-methylpropanoate
CAS No.:71015-20-8
Molecular Formula:C6H9NO2
Molecular Weight:127.143
Hs Code.:
DSSTox Substance ID:DTXSID00426069
Nikkaji Number:J228.043D
Wikidata:Q82239053
Mol file:71015-20-8.mol

Synonyms:methyl 2-isocyano-2-methylpropanoate;71015-20-8;Propanoic acid, 2-isocyano-2-methyl-, methyl ester;carbomethoxy isopropyl isonitrile;SCHEMBL10355718;DTXSID00426069;AKOS006293983;CPI;EN300-5008389

Suppliers and Price of Methyl 2-isocyano-2-methylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 17 raw suppliers

Chemical Property of Methyl 2-isocyano-2-methylpropanoate

Chemical Property:

XLogP3:0.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:127.063328530
Heavy Atom Count:9
Complexity:163

Purity/Quality:: 99% ,98%,Electron Grade , ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C(=O)OC)[N+]#[C-]

Technology Process of Methyl 2-isocyano-2-methylpropanoate

There total 4 articles about Methyl 2-isocyano-2-methylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 17746-46-2,6144-15-6
α-nitrosoisobutyrate

: 71015-20-8
2-carbomethoxy-2-methylethyl isocyanide

Guidance literature:: With triethylamine; trichlorophosphate; In dichloromethane; at 0 - 25 ℃; Inert atmosphere;

Reference yield: 64.0%

: 109862-23-9
Methyl-2-formamidoisobutyrate

: 71015-20-8
2-carbomethoxy-2-methylethyl isocyanide

Guidance literature:: With triethylamine; trichloromethyl chloroformate; In dichloromethane; 1.) -10 deg C, 30 min, 2.) r.t., 1 h;
DOI:10.1055/s-1998-2103

Reference yield:

: 60421-25-2
N-formyl-2-aminoisobutyric acid

: 71015-20-8
2-carbomethoxy-2-methylethyl isocyanide

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / ethanol; diethyl ether

2: 64 percent / Et₃N, diphosgen / CH₂Cl₂ / 1.) -10 deg C, 30 min, 2.) r.t., 1 h

With triethylamine; trichloromethyl chloroformate; In diethyl ether; ethanol; dichloromethane;
DOI:10.1055/s-1998-2103