4-[Chloro(phenyl)methanesulfonyl]morpholine

Base Information

Chemical Name:4-[Chloro(phenyl)methanesulfonyl]morpholine
CAS No.:71376-64-2
Molecular Formula:C11H14ClNO3S
Molecular Weight:275.756
Hs Code.:
DSSTox Substance ID:DTXSID50501572

Synonyms:71376-64-2;4-[Chloro(phenyl)methanesulfonyl]morpholine;DTXSID50501572

Suppliers and Price of 4-[Chloro(phenyl)methanesulfonyl]morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of 4-[Chloro(phenyl)methanesulfonyl]morpholine

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:275.0382922
Heavy Atom Count:17
Complexity:329

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1S(=O)(=O)C(C2=CC=CC=C2)Cl

Technology Process of 4-[Chloro(phenyl)methanesulfonyl]morpholine

There total 2 articles about 4-[Chloro(phenyl)methanesulfonyl]morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 71376-63-1
4-(dichloro-phenyl-methanesulfonyl)-morpholine

: 71376-64-2
α-chlorobenzyl 4-morpholinyl sulfone

Guidance literature:: With methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; N,N-dimethyl-formamide; at 40 ℃;
DOI:10.1055/s-1979-28720

Reference yield:

: 19158-31-7
4-(phenylmethane)sulfonylmorpholine

: 71376-64-2
α-chlorobenzyl 4-morpholinyl sulfone

Guidance literature:: Multi-step reaction with 2 steps

1: CCl₄, aq. NaOH, 2NEt₃>Cl

2: HMPT, MeOH, DMF / 40 °C

With methanol; tetrachloromethane; N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; N,N-dimethyl-formamide;
DOI:10.1055/s-1979-28720