3-(4-Benzoylphenyl)propanoic acid

Base Information

Chemical Name:3-(4-Benzoylphenyl)propanoic acid
CAS No.:71388-83-5
Molecular Formula:C16H14O3
Molecular Weight:254.285
Hs Code.:
DSSTox Substance ID:DTXSID40536434
Nikkaji Number:J1.400.198K
Wikidata:Q82411089

Synonyms:3-(4-benzoylphenyl)propanoic acid;71388-83-5;SCHEMBL4138253;DTXSID40536434

Suppliers and Price of 3-(4-Benzoylphenyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(4-Benzoylphenyl)propanoic acid

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:254.094294304
Heavy Atom Count:19
Complexity:310

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)CCC(=O)O

Technology Process of 3-(4-Benzoylphenyl)propanoic acid

There total 10 articles about 3-(4-Benzoylphenyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 54411-77-7
methyl p-benzoyl-2,3-dihydrocinnamate

: 71388-83-5
p-benzoyl-2,3-dihydrocinnamic acid

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; water; at 20 ℃; for 2h;
DOI:10.1002/1099-0690(200009)2000:17<3085::AID-EJOC3085>3.0.CO;2-A

Reference yield: 91.0%

: 3984-22-3
2-vinyl-1,3-dioxolane

: 90-90-4
(4-bromophenyl)(phenyl)methanone

: 71388-83-5
p-benzoyl-2,3-dihydrocinnamic acid

Guidance literature:: 2-vinyl-1,3-dioxolane; (4-bromophenyl)(phenyl)methanone; With potassium carbonate; Pd-Tedicyp catalyst; In N,N-dimethyl-formamide; at 110 ℃; for 20h;

With sodium hydroxide; water; In N,N-dimethyl-formamide; at 50 - 80 ℃;
DOI:10.1016/j.tet.2004.09.061

Reference yield:

: 6136-66-9
4-iodobenzophenone

: 71388-83-5
p-benzoyl-2,3-dihydrocinnamic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / Bu₄NCl; NaHCO₃ / Pd(OAc)2 / dimethylformamide / 3 h / 20 °C

2: 95 percent / H₂ / PtO₂ / ethyl acetate / 0.08 h / 20 °C

3: 100 percent / NaOH / dioxane; H₂O / 2 h / 20 °C

With sodium hydroxide; tetrabutyl-ammonium chloride; hydrogen; sodium hydrogencarbonate; platinum(IV) oxide; palladium diacetate; In 1,4-dioxane; water; ethyl acetate; N,N-dimethyl-formamide; 1: Heck coupling / 2: Catalytic hydrogenation / 3: Hydrolysis;
DOI:10.1002/1099-0690(200009)2000:17<3085::AID-EJOC3085>3.0.CO;2-A