2-Amino-6-(methylsulfanyl)-4-phenylpyridine-3-carbonitrile

Base Information

Chemical Name:2-Amino-6-(methylsulfanyl)-4-phenylpyridine-3-carbonitrile
CAS No.:71493-81-7
Molecular Formula:C13H11N3S
Molecular Weight:241.316
Hs Code.:
DSSTox Substance ID:DTXSID30501434
Wikidata:Q82353795

Synonyms:71493-81-7;2-Amino-6-(methylsulfanyl)-4-phenylpyridine-3-carbonitrile;DTXSID30501434

Suppliers and Price of 2-Amino-6-(methylsulfanyl)-4-phenylpyridine-3-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Amino-6-(methylsulfanyl)-4-phenylpyridine-3-carbonitrile

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:241.06736854
Heavy Atom Count:17
Complexity:292

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CSC1=NC(=C(C(=C1)C2=CC=CC=C2)C#N)N

Technology Process of 2-Amino-6-(methylsulfanyl)-4-phenylpyridine-3-carbonitrile

There total 5 articles about 2-Amino-6-(methylsulfanyl)-4-phenylpyridine-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 142232-02-8
2-Imino-6-methylthio-4-phenyl-1,2-dihydropyridin-1,3-dicarbonitril

: 71493-81-7
2-Amino-6-methylthio-4-phenyl-pyridin-3-carbonitril

Guidance literature:: With piperidine; In diethyl ether;
DOI:10.1002/ardp.19923250506

Reference yield: 62.0%

: 5447-87-0
2-(1-phenylethylidene)propanedinitrile

: 10191-60-3
dimethyl N-cyanodithioiminocarbonate

: 71493-81-7
2-Amino-6-methylthio-4-phenyl-pyridin-3-carbonitril

Guidance literature:: 2-(1-phenylethylidene)propanedinitrile; dimethyl N-cyanodithioiminocarbonate; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 6h;

With piperidine; In N,N-dimethyl-formamide; at 80 ℃;
DOI:10.1021/acs.jmedchem.0c01856

Reference yield:

: 13846-64-5
2-Cyano-3-methylthio-3-phenylacrylonitrile

: 71493-81-7
2-Amino-6-methylthio-4-phenyl-pyridin-3-carbonitril

Guidance literature:: Multi-step reaction with 2 steps

1: 45 percent / K₂CO₃ / 1,2-dimethoxy-ethane / 72 h / Ambient temperature

2: 79 percent / piperidine / diethyl ether

With piperidine; potassium carbonate; In 1,2-dimethoxyethane; diethyl ether;
DOI:10.1002/ardp.19923250506