Methyl 2,3-dihydro-3-oxo-2-(phenylmethylene)-5-benzofurancarboxylate

Base Information

Chemical Name:Methyl 2,3-dihydro-3-oxo-2-(phenylmethylene)-5-benzofurancarboxylate
CAS No.:71620-35-4
Molecular Formula:C₁₇H₁₂O₄
Molecular Weight:280.28
Hs Code.:
DSSTox Substance ID:DTXSID401160716

Synonyms:SCHEMBL10734524;DTXSID401160716;Methyl 2,3-dihydro-3-oxo-2-(phenylmethylene)-5-benzofurancarboxylate;71620-35-4

Suppliers and Price of Methyl 2,3-dihydro-3-oxo-2-(phenylmethylene)-5-benzofurancarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methyl 2,3-dihydro-3-oxo-2-(phenylmethylene)-5-benzofurancarboxylate

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:280.07355886
Heavy Atom Count:21
Complexity:448

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=CC2=C(C=C1)OC(=CC3=CC=CC=C3)C2=O

Technology Process of Methyl 2,3-dihydro-3-oxo-2-(phenylmethylene)-5-benzofurancarboxylate

There total 3 articles about Methyl 2,3-dihydro-3-oxo-2-(phenylmethylene)-5-benzofurancarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

: 100-52-7
benzaldehyde

: 71620-34-3
methyl 3-oxo-2,3-dihydrobenzofuran-5-carboxylate

: 71620-35-4
methyl 2-benzylidene-3(2H)-benzofuranone-5-carboxylate

Guidance literature:: In acetic anhydride; for 1h; Heating;

Reference yield:

: 57009-12-8
methyl 3-acetyl-4-hydroxybenzoate

: 71620-35-4
methyl 2-benzylidene-3(2H)-benzofuranone-5-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 49 percent / CuBr₂ / CHCl₃; ethyl acetate / 6 h / Heating

2: 62 percent / sodium acetate / methanol / 0.33 h / 60 °C

3: 19 percent / acetic anhydride / 1 h / Heating

With sodium acetate; copper(ll) bromide; In methanol; chloroform; acetic anhydride; ethyl acetate;

Reference yield:

: 71620-33-2
2-bromo-2'-hydroxy-5'-carbomethoxy-acetophenone

: 71620-35-4
methyl 2-benzylidene-3(2H)-benzofuranone-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / sodium acetate / methanol / 0.33 h / 60 °C

2: 19 percent / acetic anhydride / 1 h / Heating

With sodium acetate; In methanol; acetic anhydride;