2,6-Bis(5-chloro-2-hydroxybenzyl)-4-nitrophenol

Base Information

Chemical Name:2,6-Bis(5-chloro-2-hydroxybenzyl)-4-nitrophenol
CAS No.:71643-57-7
Molecular Formula:C20H15Cl2NO5
Molecular Weight:420.249
Hs Code.:
DSSTox Substance ID:DTXSID70517014
Wikidata:Q82378732

Synonyms:71643-57-7;2,6-bis(5-chloro-2-hydroxybenzyl)-4-nitrophenol;SCHEMBL11332202;DTXSID70517014;HXJBLZKZGCMPEW-UHFFFAOYSA-N;(2-hydroxy-5-nitro-1,3-phenylene)bis(methylene) bis(4-chlorophenol);2,2'-[(2-Hydroxy-5-nitro-1,3-phenylene)bis(methylene)]bis(4-chlorophenol)

Suppliers and Price of 2,6-Bis(5-chloro-2-hydroxybenzyl)-4-nitrophenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2,6-Bis(5-chloro-2-hydroxybenzyl)-4-nitrophenol

Chemical Property:

XLogP3:5.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:419.0327280
Heavy Atom Count:28
Complexity:495

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1Cl)CC2=CC(=CC(=C2O)CC3=C(C=CC(=C3)Cl)O)[N+](=O)[O-])O

Technology Process of 2,6-Bis(5-chloro-2-hydroxybenzyl)-4-nitrophenol

There total 5 articles about 2,6-Bis(5-chloro-2-hydroxybenzyl)-4-nitrophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 113393-43-4
2,6-Bis(hydroxymethyl)-4-nitrophenol

: 106-48-9,82344-39-6
4-chloro-phenol

: 71643-57-7
2,6-Bis<(5-chloro-2-hydroxyphenyl)methyl>-4-nitrophenol

Guidance literature:: In sulfuric acid; acetic acid; at 100 ℃; for 1.5h;
DOI:10.1016/S0040-4020(01)85448-X

Reference yield:

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 27694-52-6
2,6-Bis(chloromethyl)-4-nitrophenol

: 107-30-2
chloromethyl methyl ether

: 106-48-9,82344-39-6
4-chloro-phenol

: 71643-57-7
2,6-Bis<(5-chloro-2-hydroxyphenyl)methyl>-4-nitrophenol

Guidance literature:: zinc(II) chloride; In hexane; water; nitrobenzene; benzene;

Reference yield:

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 71643-57-7
2,6-Bis<(5-chloro-2-hydroxyphenyl)methyl>-4-nitrophenol

Guidance literature:: Multi-step reaction with 3 steps

1: conc. H₂SO₄ / 35 h / T >60 deg C

2: 76 percent / conc. HCl / H₂O / 7 h / Heating

3: 97 percent / acetic acid; H₂SO₄ / 1.5 h / 100 °C

With hydrogenchloride; sulfuric acid; In sulfuric acid; water; acetic acid;
DOI:10.1016/S0040-4020(01)85448-X