1,6-Bis(4-fluorophenyl)hexane-1,6-dione

Base Information

Chemical Name:1,6-Bis(4-fluorophenyl)hexane-1,6-dione
CAS No.:71825-34-8
Molecular Formula:C18H16F2O2
Molecular Weight:302.321
Hs Code.:
DSSTox Substance ID:DTXSID00502115
Wikidata:Q82354909

Synonyms:71825-34-8;1,6-BIS(4-FLUOROPHENYL)HEXANE-1,6-DIONE;SCHEMBL9680520;DTXSID00502115;DYKMRYGBFNIUPA-UHFFFAOYSA-N;1,4-bis(4-fluorobenzoyl) butane

Suppliers and Price of 1,6-Bis(4-fluorophenyl)hexane-1,6-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1,6-Bis(4-fluorophenyl)hexane-1,6-dione

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:302.11183607
Heavy Atom Count:22
Complexity:331

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)CCCCC(=O)C2=CC=C(C=C2)F)F

Technology Process of 1,6-Bis(4-fluorophenyl)hexane-1,6-dione

There total 2 articles about 1,6-Bis(4-fluorophenyl)hexane-1,6-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 1-(4-fluorophenyl)cyclopropan-1-ol

: 71825-34-8
1,6-bis(4-fluorophenyl)hexane-1,6-dione

Guidance literature:: With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; silver carbonate; In 2,2,2-trifluoroethanol; at 20 ℃; for 0.25h; Schlenk technique; Sealed tube; Inert atmosphere;
DOI:10.1021/acs.orglett.0c00967

Reference yield:

: 462-06-6
fluorobenzene

: 2035-75-8
adipic anhydride

: 71825-34-8
1,6-bis(4-fluorophenyl)hexane-1,6-dione

Guidance literature:: With aluminium trichloride; Heating;
DOI:10.1021/jm00198a006

Reference yield:

: 71825-34-8
1,6-bis(4-fluorophenyl)hexane-1,6-dione

: 88184-10-5
2,5-Bis-azepan-1-ylmethyl-1,6-bis-(4-fluoro-phenyl)-hexane-1,6-diol

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / dioxane / 10 h / Heating

2: 97.2 percent / LiAlH₄ / tetrahydrofuran; diethyl ether / 3 h

With lithium aluminium tetrahydride; In tetrahydrofuran; 1,4-dioxane; diethyl ether;
DOI:10.1007/BF00765025