2-oxo-1,2,3,4-tetrahydroquinoline-5-carbaldehyde

Base Information

Chemical Name:2-oxo-1,2,3,4-tetrahydroquinoline-5-carbaldehyde
CAS No.:72394-52-6
Molecular Formula:C10H9NO2
Molecular Weight:175.187
Hs Code.:
Mol file:72394-52-6.mol

Synonyms:1,2,3,4-tetrahydro-2-oxo-5-Quinolinecarboxaldehyde;2-Oxo-1,2,3,4-tetrahydro-quinoline-5-carbaldehyde;2-oxo-1,2,3,4-tetrahydroquinoline-5-carboxaldehyde;

Suppliers and Price of 2-oxo-1,2,3,4-tetrahydroquinoline-5-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AccelPharmtech
1,2,3,4-tetrahydro-2-oxo-5-Quinolinecarboxaldehyde 97.00%
25G
$ 7320.00

AccelPharmtech
1,2,3,4-tetrahydro-2-oxo-5-Quinolinecarboxaldehyde 97.00%
5G
$ 3900.00

AccelPharmtech
1,2,3,4-tetrahydro-2-oxo-5-Quinolinecarboxaldehyde 97.00%
1G
$ 2280.00

Total 4 raw suppliers

Chemical Property of 2-oxo-1,2,3,4-tetrahydroquinoline-5-carbaldehyde

Chemical Property:

PSA：46.17000
LogP:1.52180

Purity/Quality:

99% ^*data from raw suppliers

1,2,3,4-tetrahydro-2-oxo-5-Quinolinecarboxaldehyde 97.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-oxo-1,2,3,4-tetrahydroquinoline-5-carbaldehyde

There total 5 articles about 2-oxo-1,2,3,4-tetrahydroquinoline-5-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 726208-76-0
(1,2,3,4-tetrahydro-2-oxo-quinolin-5-yl)methanol

: 72394-52-6
1,2,3,4-tetrahydro-2-oxo-quinoline-5-aldehyde

Guidance literature:: With pyridinium chloroformate; In dichloromethane; at 20 ℃; for 8h;
DOI:10.1002/chem.200306049

Reference yield: 76.0%

: 882023-24-7
2-oxo-1,2,3,4-tetrahydroquinoline-5-carbonitrile

: 72394-52-6
1,2,3,4-tetrahydro-2-oxo-quinoline-5-aldehyde

Guidance literature:: With formic acid; Raney nickel; for 3h; Heating / reflux;

Reference yield:

: 83734-43-4
1,2-dihydro-2-oxo-5-quinolinecarboxylic acid

: 72394-52-6
1,2,3,4-tetrahydro-2-oxo-quinoline-5-aldehyde

Guidance literature:: Multi-step reaction with 4 steps

1: 75 percent / H₂; aq. NaOH / Pd/C / 240 h / 60 °C / 15001.2 Torr

2: Et₃N / tetrahydrofuran / 2 h / 0 - 20 °C

3: 0.80 g / aq. NaBH₄ / 4 h

4: 88 percent / pyridinium chloroformate / CH₂Cl₂ / 8 h / 20 °C

With sodium hydroxide; sodium tetrahydroborate; pyridinium chloroformate; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; dichloromethane;
DOI:10.1002/chem.200306049