1-Pyrrolidinecarboxylic acid, 2-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-, phenylmethyl ester, (S)-

Base Information

Chemical Name:1-Pyrrolidinecarboxylic acid, 2-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-, phenylmethyl ester, (S)-
CAS No.:72500-24-4
Molecular Formula:C20H23NO5S
Molecular Weight:389.472
Hs Code.:
Mol file:72500-24-4.mol

Synonyms:(S)-2-(toluene-4-sulfonyloxymethyl)-pyrrolidine-1-carboxylic acid benzyl ester;benzyl (S)-2-(tosyloxymethyl)pyrrolidine-1-carboxylate;S-1-(benzyloxycarbonyl)-2-[(4-methylphenylsulfonyloxy)-methyl]-pyrrolidine;(S)-carbobenzyloxypyrrolidinemethyl tosylate;(S)-N-(benzyloxycarbonyl)-2-[[(p-tolylsulfonyl)oxy]methyl]pyrrolidine;(S)-benzyl 2-((tosyloxy)methyl)pyrrolidine-1-carboxylate;

Suppliers and Price of 1-Pyrrolidinecarboxylic acid, 2-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-, phenylmethyl ester, (S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-Benzyl2-((tosyloxy)methyl)pyrrolidine-1-carboxylate 97%
1g
$ 703.00

Total 0 raw suppliers

Chemical Property of 1-Pyrrolidinecarboxylic acid, 2-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-, phenylmethyl ester, (S)-

Chemical Property:

PSA：81.29000
LogP:4.52020

Purity/Quality:: (S)-Benzyl2-((tosyloxy)methyl)pyrrolidine-1-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-Pyrrolidinecarboxylic acid, 2-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-, phenylmethyl ester, (S)-

There total 6 articles about 1-Pyrrolidinecarboxylic acid, 2-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-, phenylmethyl ester, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 6216-63-3
N-Cbz-Prolinol

: 98-59-9
p-toluenesulfonyl chloride

: 72500-24-4
(2S)-2-(4-methylphenylsulfonyloxymethyl)-pyrrolidine-1-carboxylic acid benzyl ester

Guidance literature:: With pyridine; In dichloromethane; at 0 - 20 ℃; for 18h;
DOI:10.3184/174751912X13383120111261

Reference yield:

: 1148-11-4
N-Benzyloxycarbonyl-L-proline

: 72500-24-4
(2S)-2-(4-methylphenylsulfonyloxymethyl)-pyrrolidine-1-carboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / BH₃-Me₂S

2: 98 percent / pyridine

With pyridine; dimethylsulfide borane complex;

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 72500-24-4
(2S)-2-(4-methylphenylsulfonyloxymethyl)-pyrrolidine-1-carboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂

2: pyridine / 20 °C

With pyridine; triethylamine; In dichloromethane;
DOI:10.1055/s-2005-862392