L-Prolinol

Base Information Edit

Chemical Name:L-Prolinol
CAS No.:23356-96-9
Molecular Formula:C5H11NO
Molecular Weight:101.148
Hs Code.:29221990
European Community (EC) Number:245-605-2
UNII:L5GD8LDG49
Nikkaji Number:J9.290H
Wikipedia:Prolinol
ChEMBL ID:CHEMBL1916080
Mol file:23356-96-9.mol

Synonyms:prolinol;prolinol, (+-)-isomer;prolinol, (S)-isomer

Suppliers and Price of L-Prolinol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
L-Prolinol
1g
$ 159.00

TRC
(S)-(+)-Prolinol,95%
5g
$ 110.00

TCI Chemical
L-Prolinol >97.0%(GC)(T)
25g
$ 202.00

TCI Chemical
L-Prolinol >97.0%(GC)(T)
5g
$ 67.00

SynQuest Laboratories
(S)-(+)-2-(Hydroxymethyl)pyrrolidine 99.0%
1 g
$ 16.00

SynQuest Laboratories
(S)-(+)-2-(Hydroxymethyl)pyrrolidine 99.0%
500 g
$ 576.00

SynQuest Laboratories
(S)-(+)-2-(Hydroxymethyl)pyrrolidine 99.0%
100 g
$ 157.00

Sigma-Aldrich
(S)-(+)-2-Pyrrolidinemethanol 97%
25g
$ 214.00

Sigma-Aldrich
(S)-(+)-2-Pyrrolidinemethanol 97%
1g
$ 33.40

Sigma-Aldrich
(S)-(+)-2-Pyrrolidinemethanol 97%
5g
$ 99.50

Total 196 raw suppliers

Chemical Property of L-Prolinol Edit

Chemical Property:

Appearance/Colour:Colorless to light yellow liquid
Vapor Pressure:0.0423mmHg at 25°C
Melting Point:42-44℃
Refractive Index:1.4853
Boiling Point:211 °C at 760 mmHg
PKA:14.77±0.10(Predicted)
Flash Point:86.1 °C
PSA：32.26000
Density:0.978 g/cm³
LogP:0.05950
Storage Temp.:2-8°C
Sensitive.:Air Sensitive
Solubility.:Chloroform
Water Solubility.:Fully miscible in water. Soluble in chloroform.
XLogP3:-0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:101.084063974
Heavy Atom Count:7
Complexity:56

Purity/Quality:

99% ^*data from raw suppliers

L-Prolinol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(NC1)CO
Isomeric SMILES:C1C[C@H](NC1)CO
Uses L-Prolinol is an intermediate in the synthesis of Physostigmine and Physostigmine derivative used for treatment of Alzheimer's disease. rac-Prolinol is an intermediate in the synthesis of Physostigmine and Physostigmine derivative used for treatment of Alzheimer''s disease.

Technology Process of L-Prolinol

There total 71 articles about L-Prolinol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 23356-96-9
(S)-1-Pyrrolidin-2-yl-methanol

Guidance literature:: L-proline; With lithium aluminium tetrahydride; In tetrahydrofuran; for 1.25h; Heating / reflux;

With potassium hydroxide; In tetrahydrofuran; water; for 1.25h; Heating / reflux;

Reference yield: 95.0%

: 98-79-3
L-Pyroglutamic acid

: 23356-96-9
(S)-1-Pyrrolidin-2-yl-methanol

Guidance literature:: With hydrogen; acetic acid; In water; at 100 ℃; for 20h; under 52505.3 Torr; Pressure; Temperature; Reagent/catalyst; Time; Autoclave;