1,8-Nonadiene-3,7-dione, 1,9-dihydroxy-5-(4-methylphenyl)-1,9-diphenyl-

Base Information

• Chemical Name: 1,8-Nonadiene-3,7-dione, 1,9-dihydroxy-5-(4-methylphenyl)-1,9-diphenyl-
• CAS No.: 72610-58-3
• Molecular Formula: C28H26O4
• Molecular Weight: 426.512
• Mol file: 72610-58-3.mol

Synonyms:

Chemical Property of 1,8-Nonadiene-3,7-dione, 1,9-dihydroxy-5-(4-methylphenyl)-1,9-diphenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,8-Nonadiene-3,7-dione, 1,9-dihydroxy-5-(4-methylphenyl)-1,9-diphenyl-

There total 1 articles about 1,8-Nonadiene-3,7-dione, 1,9-dihydroxy-5-(4-methylphenyl)-1,9-diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methyl-benzaldehyde (104-87-0) + 1-phenylbutan-1,3-dione (93-91-4) → 1,9-diphenyl-5-(p-tolyl)-1,3,7,9-nonanetetraone enol form (72610-58-3) + p-Toluic acid (99-94-5)

Guidance literature:

With potassium hydride; Yield given. Multistep reaction. Yields of byproduct given; 1) THF, 20-30 deg C, 1 h; 2) THF, 1 h;

DOI:10.1021/jo01294a032

Reference yield: 26.0%

1,9-diphenyl-5-(p-tolyl)-1,3,7,9-nonanetetraone enol form (72610-58-3) → 2-Benzoyl-3-(2-oxo-2-phenyl-ethyl)-5-p-tolyl-cyclohex-2-enone (72610-60-7)

Guidance literature:

With silica gel; In benzene; for 1h; Heating;

DOI:10.1021/jo01294a032

Reference yield:

nickel(II) acetate tetrahydrate (6018-89-9) + 5-p-methylphenyl-1,9-diphenyl-1,3,7,9-nonantetraone (72610-58-3) → Ni(2+)*OC(C6H5)CHC(O)CH2CH(C6H4CH3)CH2C(O)CHC(C6H5)O(2-) = Ni(OC(C6H5)CHCOCH2CH(C6H4CH3)CH2COCHC(C6H5)O)

Guidance literature:

With KOH; In methanol; to a soln. of organic compound in MeOH at 25°C added Ni-salt in MeOH dropwise over a period of one hour, KOH added, mixture stirred and refuxed at 60°C for 10 h, cooled in ice bath, distilled water added; filtered, dried in vac. at 50°C for 48 h, recrystd. from CHCl3, dried at 50°C for 48 h; elem. anal.;

DOI:10.1016/0022-1902(80)80282-X

upstream raw materials:

4-methyl-benzaldehyde

1-phenylbutan-1,3-dione

Downstream raw materials:

2-Benzoyl-3-(2-oxo-2-phenyl-ethyl)-5-p-tolyl-cyclohex-2-enone