Benzenamine, 4-methoxy-N-(1-methylheptyl)-

Base Information

• Chemical Name: Benzenamine, 4-methoxy-N-(1-methylheptyl)-
• CAS No.: 726-23-8
• Molecular Formula: C15H25NO
• Molecular Weight: 235.37
• Mol file: 726-23-8.mol

Synonyms:

Chemical Property of Benzenamine, 4-methoxy-N-(1-methylheptyl)-

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenamine, 4-methoxy-N-(1-methylheptyl)-

There total 11 articles about Benzenamine, 4-methoxy-N-(1-methylheptyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

rac-octan-2-ol (4128-31-8,113301-48-7,4128-32-9) + 4-methoxy-aniline (104-94-9) → N-(4-methoxyphenyl)-2-aminooctane (726-23-8)

Guidance literature:

With trimethylamine-N-oxide; [bis(hexamethylene)cyclopentadienone]iron tricarbonyl; In toluene; at 150 ℃; for 24h; Time; Inert atmosphere; Schlenk technique; Molecular sieve; Sealed tube;

DOI:10.1055/s-0039-1690101

Reference yield: 99.0%

N-(2-octylidene)-4-methoxyaniline (368866-47-1) → N-(4-methoxyphenyl)-2-aminooctane (726-23-8)

Guidance literature:

With trimethylamine-N-oxide; [bis(hexamethylene)cyclopentadienone]iron tricarbonyl; isopropyl alcohol; at 100 ℃; for 18h; Sealed tube; Inert atmosphere;

DOI:10.1002/ejoc.201801348

Reference yield: 98.0%

4-methoxy-aniline (104-94-9) + hexyl-methyl-ketone (111-13-7) → N-(4-methoxyphenyl)-2-aminooctane (726-23-8)

Guidance literature:

With formic acid; 4-methoxy-N-(1-(naphthalen-2-yl)ethylidene)aniline; sodium formate; In water; at 80 ℃; for 2h; pH=4.8; Sealed tube; Inert atmosphere;

DOI:10.1002/chem.201204194

upstream raw materials:

N-(2-octylidene)-4-methoxyaniline

n-octyne

4-methoxy-aniline

hexyl-methyl-ketone

Refernces

• 1、 Aiolfi, Francesco,Bai, Xishan,Cettolin, Mattia,Dal Corso, Alberto,Gennari, Cesare,Piarulli, Umberto,Pignataro, Luca. "Hydrogen-Borrowing Amination of Secondary Alcohols Promoted by a (Cyclopentadienone)iron Complex". . p. 3545 - 3555. Retrieved 2019/09/09.
• 2、 Facchini, Sofia Vailati,Cettolin, Mattia,Bai, Xishan,Casamassima, Giuseppe,Pignataro, Luca,Gennari, Cesare,Piarulli, Umberto. "Efficient Synthesis of Amines by Iron-Catalyzed C=N Transfer Hydrogenation and C=O Reductive Amination". supporting information. p. 1054 - 1059. Retrieved 2018/01/27.