1-(4-(3-Aminophenyl)thiazol-2-yl)guanidine

Base Information

Chemical Name:1-(4-(3-Aminophenyl)thiazol-2-yl)guanidine
CAS No.:72801-60-6
Molecular Formula:C10H11N5S
Molecular Weight:233.297
Hs Code.:
ChEMBL ID:CHEMBL359267
DSSTox Substance ID:DTXSID00993605
Nikkaji Number:J276.558F
Mol file:72801-60-6.mol

Synonyms:72801-60-6;1-(4-(3-Aminophenyl)thiazol-2-yl)guanidine;2-[4-(3-aminophenyl)-1,3-thiazol-2-yl]guanidine;2-guanidino-4-(3-aminophenyl)thiazole;4-(3-Aminophenyl)-2-guanidinothiazole;CHEMBL359267;SCHEMBL2393684;SCHEMBL10672113;DTXSID00993605;QDNHJPYZKZDMNJ-UHFFFAOYSA-N;2-guanidino-4-(3-aminophenyl)-thiazole;3-(2-guanidino-4-thiazolyl)benzeneamine;2-guanidino-4-(3-amino-phenyl)-thiazole;N-[4-(3-Aminophenyl)-1,3-thiazol-2-yl]guanidine

Suppliers and Price of 1-(4-(3-Aminophenyl)thiazol-2-yl)guanidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1-(4-(3-Aminophenyl)thiazol-2-yl)guanidine

Chemical Property:

PSA：131.55000
LogP:3.27900
XLogP3:1.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:233.07351655
Heavy Atom Count:16
Complexity:266

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)N)C2=CSC(=N2)N=C(N)N

Technology Process of 1-(4-(3-Aminophenyl)thiazol-2-yl)guanidine

There total 5 articles about 1-(4-(3-Aminophenyl)thiazol-2-yl)guanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 83831-32-7
2-guanidino-4-(3-nitrophenyl)thiazole

: 72801-60-6
2-guanidino-4-(3-aminophenyl)thiazole

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol; for 4h; under 2585.7 Torr;
DOI:10.1021/jm00356a005

Reference yield:

: ethyl N-[3-(2-guanidino-4-thiazolyl)-phenyl]-carbamate hydrobromide

: 145066-50-8,72801-60-6
2-guanidino-4-(3-aminophenyl)thiazole

Guidance literature:: With potassium hydroxide; In ethanol; water;

Reference yield:

: 2227-64-7
3'-nitro-2-bromoacetophenone

: 72801-60-6
2-guanidino-4-(3-aminophenyl)thiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 59 percent / triethylamine / methanol / Ambient temperature

2: 85 percent / H₂, concd. HCl / 10percent Pd/C / ethanol / 4 h / 2585.7 Torr

With hydrogenchloride; hydrogen; triethylamine; palladium on activated charcoal; In methanol; ethanol;
DOI:10.1021/jm00356a005