83831-32-7 Usage
Uses
Used in Antimicrobial Applications:
2-guanidino-4-(3-nitrophenyl)thiazole is used as an antimicrobial agent for its potential to combat various microorganisms. Its ability to inhibit microbial growth makes it a candidate for further research and development in the field of infectious diseases.
Used in Enzyme Inhibition:
In the pharmaceutical industry, 2-guanidino-4-(3-nitrophenyl)thiazole is used as an enzyme inhibitor targeting enzymes such as aldose reductase and xanthine oxidase. Its inhibitory effects on these enzymes could be leveraged for the development of therapeutic agents to treat related conditions.
Used in Biochemical Research:
2-guanidino-4-(3-nitrophenyl)thiazole is used as a fluorescence probe for detecting cysteine in biological samples. Its fluorescent properties allow for the sensitive and selective detection of this important amino acid, which is crucial for various biological processes.
These applications highlight the versatility of 2-guanidino-4-(3-nitrophenyl)thiazole and underscore the need for continued research to fully explore its potential in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 83831-32-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,3,8,3 and 1 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 83831-32:
(7*8)+(6*3)+(5*8)+(4*3)+(3*1)+(2*3)+(1*2)=137
137 % 10 = 7
So 83831-32-7 is a valid CAS Registry Number.
83831-32-7Relevant academic research and scientific papers
Arylbiamidines: Synthesis and structural studies en route to anticancer applications
Grytsai, Oleksandr,Gon?alves, Leticia Christina Pires,Bardovskyi, Rostyslav,Hamouda-Tekaya, Nedra,Rocchi, Stéphane,Ronco, Cyril,Benhida, Rachid
supporting information, p. 11893 - 11897 (2021/07/21)
Biamidines are a unique and poorly studied class of nitrogenous compounds prone to tautomerization and H-bonding. Four series of heteroaryl diarylbiamidines were synthesized and the antimelanoma activity and physicochemical properties of the resulting 37 new compounds were evaluated. The dimethylthiazolyl 3-bromophenyl biamidine derivative B6 inhibits the growth of six different melanoma cell lines, having higher activity than the positive control drug, the B-RAF inhibitor PLX4032. This study introduces diarylbiamidines as promising frameworks for drug discovery.
Conformational requirements for histamine H2-receptor inhibitors: A structure-activity study of phenylene analogues related to cimetidine and tiotidine
Hoffman,Pietruszkiewicz,Habecker,Phillips,Bolhofer,Cragoe Jr.,Torchiana,Lumma Jr.,Baldwin
, p. 140 - 144 (2007/10/02)
Two series of compounds related to cimetidine and tiotidine were synthesized as part of a study to evaluate the importance of conformational parameters in binding at histamine H2 receptors. The flexible methylthioethyl connecting chain was repl
