Ethyl 4-amino-5-cyano-2-hydroxy-3-methylbenzoate

Base Information

Chemical Name:Ethyl 4-amino-5-cyano-2-hydroxy-3-methylbenzoate
CAS No.:72817-85-7
Molecular Formula:C11H12N2O3
Molecular Weight:220.228
Hs Code.:2926909090
DSSTox Substance ID:DTXSID60379340
Wikidata:Q82169100
Mol file:72817-85-7.mol

Synonyms:ethyl 4-amino-5-cyano-2-hydroxy-3-methylbenzoate;72817-85-7;4-Amino-5-cyano-2-hydroxy-3-methyl-benzoic acid ethyl ester;Benzoic acid, 4-amino-5-cyano-2-hydroxy-3-methyl-, ethyl ester;Ethyl4-amino-5-cyano-2-hydroxy-3-methylbenzoate;SCHEMBL996696;DTXSID60379340;AREVECVPDJASFB-UHFFFAOYSA-N;CS-M1668;XCA81785;AKOS016007368;SB79609;TS-00498;A914700;4-Amino-5-cyano-2-hydroxy-3-methylbenzoic acid ethyl ester;Benzoic acid,4-aMino-5-cyano-2-hydroxy-3-Methyl-,ethyl ester

Suppliers and Price of Ethyl 4-amino-5-cyano-2-hydroxy-3-methylbenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Ethyl 4-amino-5-cyano-2-hydroxy-3-methylbenzoate 97%
1g
$ 1110.00

Crysdot
Ethyl4-amino-5-cyano-2-hydroxy-3-methylbenzoate 95+%
5g
$ 297.00

Crysdot
Ethyl4-amino-5-cyano-2-hydroxy-3-methylbenzoate 95+%
10g
$ 495.00

ChemScene
Benzoicacid,4-amino-5-cyano-2-hydroxy-3-methyl-,ethylester
250mg
$ 86.00

Alichem
Ethyl4-amino-5-cyano-2-hydroxy-3-methylbenzoate
10g
$ 495.00

Alichem
Ethyl4-amino-5-cyano-2-hydroxy-3-methylbenzoate
5g
$ 294.00

AK Scientific
Ethyl4-amino-5-cyano-2-hydroxy-3-methylbenzoate
250mg
$ 157.00

Total 8 raw suppliers

Chemical Property of Ethyl 4-amino-5-cyano-2-hydroxy-3-methylbenzoate

Chemical Property:

PSA：96.34000
LogP:1.91238
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:220.08479225
Heavy Atom Count:16
Complexity:310

Purity/Quality:

97% ^*data from raw suppliers

Ethyl 4-amino-5-cyano-2-hydroxy-3-methylbenzoate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(C(=C(C(=C1)C#N)N)C)O

Technology Process of Ethyl 4-amino-5-cyano-2-hydroxy-3-methylbenzoate

There total 2 articles about Ethyl 4-amino-5-cyano-2-hydroxy-3-methylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 123-06-8
Ethoxymethylenemalononitrile

: 72817-85-7
4-Amino-5-cyan-3-methyl-salicylsaeure-ethylester

Guidance literature:: ethyl propanoylacetate; With sodium ethanolate; at 20 ℃; for 12h;

Ethoxymethylenemalononitrile; at 20 - 80 ℃; for 2h;

With hydrogenchloride; water; pH=7;

Reference yield: 59.0%

: 123-06-8
Ethoxymethylenemalononitrile

: 4949-44-4
ethyl propanoylacetate

: 72817-85-7
4-Amino-5-cyan-3-methyl-salicylsaeure-ethylester

Guidance literature:: ethyl propanoylacetate; With sodium ethanolate; In ethanol; at 0 - 20 ℃;

Ethoxymethylenemalononitrile; In ethanol; at 20 - 80 ℃; for 2h;

With hydrogenchloride; water; In ethanol; pH=7;

Reference yield: 95.0%

: 72817-85-7
4-Amino-5-cyan-3-methyl-salicylsaeure-ethylester

: 72817-94-8
4-amino-5-cyano-2-hydroxy-3-methylbenzoic acid

Guidance literature:: 4-Amino-5-cyan-3-methyl-salicylsaeure-ethylester; With lithium hydroxide; ethanol; water; at 20 - 80 ℃; for 4h; Heating / reflux;

With hydrogenchloride; water; pH=5;