1-(4-Iodobutyl)-4-methoxybenzene

Base Information

• Chemical Name: 1-(4-Iodobutyl)-4-methoxybenzene
• CAS No.: 73515-08-9
• Molecular Formula: C11H15IO
• Molecular Weight: 290.144
• NSC Number: 141201
• DSSTox Substance ID: DTXSID90301119
• Wikidata: Q82044710
• Mol file: 73515-08-9.mol

Synonyms:1-(4-iodobutyl)-4-methoxybenzene;73515-08-9;NSC141201;SCHEMBL5045835;DTXSID90301119;GDXQOJQCDWXWKG-UHFFFAOYSA-N;1-iodo-4-(4-methoxyphenyl)butane;1-(4-Iodo-butyl)-4-methoxy-benzene;AB93406;NSC-141201

Chemical Property of 1-(4-Iodobutyl)-4-methoxybenzene

Chemical Property:

• Vapor Pressure: 0.00061mmHg at 25°C
• Boiling Point: 320°Cat760mmHg
• Flash Point: 147.4°C
• Density: 1.464g/cm³
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 290.01676
• Heavy Atom Count: 13
• Complexity: 119

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)CCCCI

Technology Process of 1-(4-Iodobutyl)-4-methoxybenzene

There total 3 articles about 1-(4-Iodobutyl)-4-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-(4-methoxyphenyl)butan-1-ol (52244-70-9,239474-80-7) → 1-iodo-4-(4-methoxyphenyl)butane (73515-08-9)

Guidance literature:

With 1H-imidazole; iodine; triphenylphosphine; In dichloromethane; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1002/anie.201905986

Reference yield: 97.0%

1-(4-bromo-butyl)-4-methoxy-benzene (35191-43-6) → 1-iodo-4-(4-methoxyphenyl)butane (73515-08-9)

Guidance literature:

With sodium iodide; In acetone; for 1h; Heating / reflux;

Reference yield:

1H-imidazole (288-32-4) + 4-(4-methoxyphenyl)butan-1-ol (52244-70-9,239474-80-7) → 1-iodo-4-(4-methoxyphenyl)butane (73515-08-9)

Guidance literature:

With I₂; triphenylphosphine; In hexane; dichloromethane; toluene;

upstream raw materials:

4-(4-methoxyphenyl)butan-1-ol

1-(4-bromo-butyl)-4-methoxy-benzene

1H-imidazole

Downstream raw materials:

[6-(4-methoxy-phenyl)-hex-1-ynyl]-trimethyl-silane

3-[4-(4-Methoxyphenyl)butyloxy]-6-methyl-2-pyridine carboxaldehyde

4-(4-Nitro-butyl)-phenol

3-{6-(2-Methoxycarbonyl-ethyl)-5-[4-(4-methoxy-phenyl)-butoxy]-pyridin-2-ylmethylsulfanylmethyl}-benzoic acid methyl ester

Refernces

• 1、 Hernán-Gómez, Alberto,Rodríguez, Mònica,Parella, Teodor,Costas, Miquel. "Electrophilic Iron Catalyst Paired with a Lithium Cation Enables Selective Functionalization of Non-Activated Aliphatic C?H Bonds via Metallocarbene Intermediates". supporting information. p. 13904 - 13911. Retrieved 2019/08/30.
• 2、 -. "Novel pentafluorosulfanyl compounds". Page/Page column 15-16. . Retrieved 2010/02/13.