3-Methyl-2-phenylisoquinolin-1(2H)-one

Base Information

Chemical Name:3-Methyl-2-phenylisoquinolin-1(2H)-one
CAS No.:73109-01-0
Molecular Formula:C16H13NO
Molecular Weight:235.285
Hs Code.:
DSSTox Substance ID:DTXSID20502516
Nikkaji Number:J2.411.209H
Wikidata:Q82355628

Synonyms:3-Methyl-2-phenylisoquinolin-1(2H)-one;73109-01-0;DTXSID20502516

Suppliers and Price of 3-Methyl-2-phenylisoquinolin-1(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-Methyl-2-phenylisoquinolin-1(2H)-one

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:235.099714038
Heavy Atom Count:18
Complexity:354

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=CC=CC=C2C(=O)N1C3=CC=CC=C3

Technology Process of 3-Methyl-2-phenylisoquinolin-1(2H)-one

There total 9 articles about 3-Methyl-2-phenylisoquinolin-1(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: C₁₆H₁₄BrNO₂

: 73109-01-0
3-methyl-2-phenylisoquinolin-1(2H)-one

Guidance literature:: With titanium(IV) isopropylate; 1,1,3,3-Tetramethyldisiloxane; triethylamine; 3-Methyl-1-phenyl-2-phospholene 1-oxide; In toluene; at 110 ℃;
DOI:10.1002/ejoc.201601628

Reference yield: 56.0%

: 918867-73-9
2-cyclopropyl-N-phenylbenzamide

: 73109-01-0
3-methyl-2-phenylisoquinolin-1(2H)-one

: 53890-83-8
2-phenyl-3,3-dimethylisoindoline-1-one

Guidance literature:: With p-benzoquinone; dichloro bis(acetonitrile) palladium(II); In 1,4-dioxane; at 80 ℃; for 12h;
DOI:10.1021/ol062476e

Reference yield:

: 2-cyclopropylbenzoyl chloride

: 73109-01-0
3-methyl-2-phenylisoquinolin-1(2H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / triethylamine / CH₂Cl₂

2: 56 percent / benzoquinone / PdCl₂(MeCN)2 / dioxane / 12 h / 80 °C

With triethylamine; p-benzoquinone; dichloro bis(acetonitrile) palladium(II); In 1,4-dioxane; dichloromethane;
DOI:10.1021/ol062476e