3-BENZHYDRYLIDENE-2-METHYL-1-PYRROLINE

Base Information

• Chemical Name: 3-BENZHYDRYLIDENE-2-METHYL-1-PYRROLINE
• CAS No.: 731-36-2
• Molecular Formula: C₁₈H₁₇N
• Molecular Weight: 247.34
• Mol file: 731-36-2.mol

Synonyms:4-benzhydrylidene-5-methyl-3,4-dihydro-2H-pyrrole;3-BENZHYDRYLIDENE-2-METHYL-1-PYRROLINE;2H-Pyrrole,4-(diphenylmethylene)-3,4-dihydro-5-methyl;3-(Diphenyl-methylen)-2-methyl-1-pyrrolin;2-Methyl-3-diphenylmethylen-1-pyrrolin;

Chemical Property of 3-BENZHYDRYLIDENE-2-METHYL-1-PYRROLINE

Chemical Property:

• PSA: 12.36000
• LogP: 3.78870

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-BENZHYDRYLIDENE-2-METHYL-1-PYRROLINE

There total 2 articles about 3-BENZHYDRYLIDENE-2-METHYL-1-PYRROLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

diphenylmethylenecyclopropene (7632-57-7) + acetonitrile (75-05-8,26809-02-9) → 4-benzhydrylidene-5-methyl-3,4-dihydro-2H-pyrrole (731-36-2) + N-(4,4-diphenyl-3-butenyl)acetamide

Guidance literature:

With trifluorormethanesulfonic acid; In dichloromethane; at 25 ℃; for 0.5h; Further Variations:; Solvents; Product distribution;

DOI:10.1055/s-2004-832838

Reference yield:

→ 4-benzhydrylidene-5-methyl-3,4-dihydro-2H-pyrrole (731-36-2)

Guidance literature:

1,1-Diphenylbutan-1,4-diol, Acetonitril, POCl3, SnCl4, 130-140grad;

DOI:10.1248/cpb.14.187

upstream raw materials:

diphenylmethylenecyclopropene

acetonitrile

Refernces

• 1、 Ohki,Hamaguchi,Yanagi,Yoshino. "Cyclization towards carbon-carbon double bond. 3. A new synthesis of 1-pyrroline derivatives and a synthesis of 1,2-dialkyl-3-diphenylmethylenepyrrolidine alkyl halide, an anti-acetylcholine substance.". . p. 187 - 193. Retrieved 2007/10/07.