7632-57-7

Basic information

• Product Name: Benzene, 1,1'-(cyclopropylidenemethylene)bis-
• CAS NO: 7632-57-7
• Molecular Formula: C16H14
• Molecular Weight: 206.287
• Mol File: 7632-57-7.mol
• Article Data: 29

Chemical Properties

• Melting Point: 64.5-65.5 °C
• Boiling Point: 110-114 °C
• Density: 1.0260 g/cm3(Temp: 14 °C)
• CAS DataBase Reference: Benzene, 1,1'-(cyclopropylidenemethylene)bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-(cyclopropylidenemethylene)bis-(7632-57-7)
• EPA Substance Registry System: Benzene, 1,1'-(cyclopropylidenemethylene)bis-(7632-57-7)

Safety Data

• Hazardous Substances Data: 7632-57-7(Hazardous Substances Data)

Upstream product

• 119-61-9 benzophenone 
• 14114-05-7 cyclopropyltriphenylphosphonium bromide 
• 65006-97-5 [(1-chlorocyclopropyl)sulfinyl]benzene 
• 23719-80-4 cyclopropylmagnesium bromide 
• 7333-63-3 4-bromobutylphosphonium bromide 
• 688358-89-6 pentachlorophenyl cyclopropyl sulfone 
• 50337-59-2 cyclopropyl phenyl sulfoxide 
• 14633-54-6 cyclopropylphenylsulfide 
• 266328-24-9 tert-butyl diphenylcyclopropylperoxyacetate 
• 3607-17-8 3-bromopropyltriphenylphosphonium bromide 
• 109-64-8 1,3-dibromo-propane 
• 115413-58-6 [1-(Diphenyl-phosphinoyl)-cyclopropyl]-diphenyl-methanol 
• 14633-95-5 triphenylphosphonium cyclopropylide 

Downstream Products

• 33962-05-9 C₂₂H₁₄N₄ 
• 56152-83-1 1,1-Dichlor-2,2-diphenylspiropentan 
• 51752-45-5 1-diphenylmethylcyclopropanol 
• 5785-66-0 cyclopropyl diphenyl carbinol 
• 24104-20-9 2,2-diphenylcyclobutanone 
• 5746-99-6 cyclopropyldiphenylmethane 
• 51752-42-2 (1-bromo-cyclopropyl)-diphenyl-methanol 
• 51752-40-0 2,4-dibromo-1,1-diphenylbut-1-ene 
• 24321-71-9 Trifluoressigsaeure-<4,4-diphenyl-buten-(3)-yl-(1)>-ester 
• 89683-70-5 (1S,2R)-4-Benzhydrylidene-cyclopentane-1,2-dicarboxylic acid diethyl ester 
• 89683-67-0 (1S,2S)-4-Benzhydrylidene-cyclopentane-1,2-dicarboxylic acid diethyl ester 
• 82432-06-2 C₁₉H₂₀ 
• 7714-72-9 6,6-diphenylfulvene 
• 142428-13-5 5,5-dichloro-6,6-diphenylspiro<2,3>hexan-4-one 

Relevant articles and documents

Gem-Difluorination of Methylenecyclopropanes (MCPs) Featuring a Wagner-Meerwein Rearrangement: Synthesis of 2-Arylsubstituted gem-Difluorocyclobutanes

The geminal difluorocyclobutane core is a valuable structural element in medicinal chemistry. Strategies for gem-difluorocyclobutanes, especially the 2-substituted cases, are limiting and often suffer from harsh reaction conditions. Reported herein is a m

Ring opening of methylenecyclopropanes with halides in liquid sulfur dioxide

Methylenecyclopropanes (MCP) undergo ring opening reactions with group I and II metal halides and ammonium halides in liquid SO2 to afford homoallylic halides, which are versatile reagents in organic synthesis. The developed reaction conditions are compatible with acid-labile substrates such as N-Boc-protected compounds. Liquid SO2 is a polar reaction medium with Lewis acid properties that solubilizes inorganic salts. The unique properties of SO2 were demonstrated by control experiments: 1) upon performing the reactions with the aforementioned salts in conventional solvents, the MCP ring opening was not observed either in the presence of catalytic amounts of H3PO4 (similar pKa to that of H2SO3), or in the absence of H3PO4; 2) a solution of SO2 in THF exhibited similar properties to that of liquid SO2.

Highly Enantioselective Construction of Strained Spiro[2,3]hexanes through a Michael Addition/Ring Expansion/Cyclization Cascade

We herein report a general organocatalytic enantioselective strategy for the construction of highly strained spiro[2,3]hexane skeletons from methylenecyclopropanes and a broad selection of α,β-unsaturated aldehydes. The reaction proceeds through a Michael addition followed by ring expansion of methylenecyclopropanes and nucleophilic attack of an enamine to realize the construction of spiro[2,3]hexanes. Key to the success of this approach are the utilization of an electron-deficient difluoro-substituted secondary amine catalyst and the intrinsic reactivity of methylenecyclopropanes.