Technology Process of Bicyclo[3.1.0]hexane-1-carboxylic acid,
6-ethenyl-2-oxo-3-(phenylseleno)-, methyl ester
There total 6 articles about Bicyclo[3.1.0]hexane-1-carboxylic acid,
6-ethenyl-2-oxo-3-(phenylseleno)-, methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium diisopropyl amide;
In
tetrahydrofuran;
at -78 ℃;
DOI:10.1021/jo01297a056
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 84 percent / lithium diisopropylamide / tetrahydrofuran / 0.08 h / 0 °C
2: 99 percent / p-toluenesulfonyl azide, triethylamine / acetonitrile / 24 h / Ambient temperature
3: 64 percent / copper(II) acetylacetonate / toluene / 3 h / Heating
4: 69 percent / lithium diisopropylamide / tetrahydrofuran; hexamethylphosphoric acid triamide / 0.08 h / -78 °C
With
copper acetylacetonate; 4-toluenesulfonyl azide; triethylamine; lithium diisopropyl amide;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; toluene; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 99 percent / p-toluenesulfonyl azide, triethylamine / acetonitrile / 24 h / Ambient temperature
2: 64 percent / copper(II) acetylacetonate / toluene / 3 h / Heating
3: 69 percent / lithium diisopropylamide / tetrahydrofuran; hexamethylphosphoric acid triamide / 0.08 h / -78 °C
With
copper acetylacetonate; 4-toluenesulfonyl azide; triethylamine; lithium diisopropyl amide;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; toluene; acetonitrile;
