3-(Chloromethyl)-5-(4-nitrophenyl)-1,2,4-oxadiazole

Base Information

Chemical Name:3-(Chloromethyl)-5-(4-nitrophenyl)-1,2,4-oxadiazole
CAS No.:73217-32-0
Molecular Formula:C9H6ClN3O3
Molecular Weight:239.618
Hs Code.:
DSSTox Substance ID:DTXSID70502905
Wikidata:Q82356307

Synonyms:73217-32-0;3-(chloromethyl)-5-(4-nitrophenyl)-1,2,4-oxadiazole;SCHEMBL7566386;DTXSID70502905

Suppliers and Price of 3-(Chloromethyl)-5-(4-nitrophenyl)-1,2,4-oxadiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-(Chloromethyl)-5-(4-nitrophenyl)-1,2,4-oxadiazole

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:239.0097688
Heavy Atom Count:16
Complexity:253

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=NC(=NO2)CCl)[N+](=O)[O-]

Technology Process of 3-(Chloromethyl)-5-(4-nitrophenyl)-1,2,4-oxadiazole

There total 1 articles about 3-(Chloromethyl)-5-(4-nitrophenyl)-1,2,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 122-04-3
4-nitro-benzoyl chloride

: 3272-96-6
2-chloro-N-hydroxyethanimidamide

: 73217-32-0
3-chloromethyl-5-(4-nitro-phenyl)-[1,2,4]oxadiazole

Guidance literature:

Reference yield: 88.0%

: 1147550-11-5
ammonium thiocyanate

: 73217-32-0
3-chloromethyl-5-(4-nitro-phenyl)-[1,2,4]oxadiazole

: 96898-43-0
5-(4-nitrophenyl)-3-(thiocyanatomethyl)-1,2,4-oxadiazole

Guidance literature:: In dimethyl sulfoxide; for 1h; Heating;
DOI:10.1021/jm00147a019

Reference yield:

: 73217-32-0
3-chloromethyl-5-(4-nitro-phenyl)-[1,2,4]oxadiazole

: 73217-54-6
N,N-dimethyl-N'-[5-(4-nitro-phenyl)-[1,2,4]oxadiazol-3-ylmethylene]-benzene-1,4-diamine N'-oxide

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / Heating

2: aq. NaOH / ethanol

With sodium hydroxide; In ethanol;