3-Methylenecyclobutylacetate

Base Information

• Chemical Name: 3-Methylenecyclobutylacetate
• CAS No.: 18218-27-4
• Molecular Formula: C7H10O2
• Molecular Weight: 126.1531
• DSSTox Substance ID: DTXSID20171261
• Nikkaji Number: J1.223.086I
• Wikidata: Q83041352
• Mol file: 18218-27-4.mol

Synonyms:3-Methylenecyclobutylacetate;18218-27-4;3-methylidenecyclobutylacetate;3-methylidenecyclobutyl acetate;SCHEMBL9146956;DTXSID20171261

Chemical Property of 3-Methylenecyclobutylacetate

Chemical Property:

• Vapor Pressure: 5.38mmHg at 25°C
• Boiling Point: 143.2°Cat760mmHg
• Flash Point: 29.6°C
• Density: 1.01g/cm³
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 126.068079557
• Heavy Atom Count: 9
• Complexity: 141

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)OC1CC(=C)C1

Technology Process of 3-Methylenecyclobutylacetate

There total 5 articles about 3-Methylenecyclobutylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-acetoxy-3-chloromercurio-1-methylenecyclobutane → 3-acetoxy-1-methylenecyclobutane (18218-27-4)

Guidance literature:

With sodium tetrahydroborate; In methanol;

Reference yield:

[1.1.1]propellane (35634-10-7) + acetic acid (64-19-7,77671-22-8) → 3-acetoxy-1-methylenecyclobutane (18218-27-4)

Guidance literature:

DOI:10.1021/ja00383a046

Reference yield:

acetic acid (64-19-7,77671-22-8) + spiro[2.2]pentan-2-amine hydrochloride (17202-70-9) → 3-acetoxy-1-methylenecyclobutane (18218-27-4) + 2-acetoxy-1-methylenecyclobutane + spiropentyl acetate

Guidance literature:

With sodium nitrite; for 2h;

DOI:10.1021/jo990654u

upstream raw materials:

[1.1.1]propellane

acetic acid

Tricyclo<1.1.1.0^1,3>pentan

spiro[2.2]pentan-2-amine hydrochloride