2-ETHOXYBENZYLMAGNESIUM CHLORIDE

Base Information

• Chemical Name: 2-ETHOXYBENZYLMAGNESIUM CHLORIDE
• CAS No.: 738580-60-4
• Molecular Formula: C9H11ClMgO
• Molecular Weight: 195.94900
• Mol file: 738580-60-4.mol

Synonyms:2-ethoxybenzyl magnesium chloride;2-Ethoxybenzylmagnesium chloride 0.25 M in Tetrahydrofuran;

Chemical Property of 2-ETHOXYBENZYLMAGNESIUM CHLORIDE

Chemical Property:

• PSA: 9.23000
• LogP: -0.64640

Purity/Quality:

97% ^*data from raw suppliers

2-Ethoxybenzylmagnesiumchloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-ETHOXYBENZYLMAGNESIUM CHLORIDE

There total 1 articles about 2-ETHOXYBENZYLMAGNESIUM CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-chloromethyl-2-ethoxybenzene (60906-78-7) → 2-ethoxybenzyl magnesium chloride (738580-60-4)

Guidance literature:

With iodine; magnesium; In tetrahydrofuran; for 2h; Heating / reflux;

Reference yield:

2-ethoxybenzyl magnesium chloride (738580-60-4) + 3-methyl-1-[4-(phenylmethyl)morpholin-2-yl]butan-1-one (852237-37-7) → 1-[2-(ethyloxy)phenyl]-4-methyl-2-[4-(phenylmethyl)morpholin-2-yl]pentan-2-ol (852236-54-5)

Guidance literature:

2-ethoxybenzyl magnesium chloride; 3-methyl-1-[4-(phenylmethyl)morpholin-2-yl]butan-1-one; In tetrahydrofuran; diethyl ether; at 0 - 20 ℃; for 0.5h;

With water; In tetrahydrofuran; diethyl ether;

Reference yield:

1-tert-butyl 4-[1H-1,2,3-benzotriazol-1-yl (phenyl) methyl]piperazine-1-carboxylate (860302-53-0) + 2-ethoxybenzyl magnesium chloride (738580-60-4) → 1-[2-(2-ethoxy-phenyl)-1-phenyl-ethyl]-piperazine (860302-52-9)

Guidance literature:

In tetrahydrofuran; at -78 - 0 ℃; for 1.5h;

upstream raw materials:

1-chloromethyl-2-ethoxybenzene

Downstream raw materials:

1-[2-(ethyloxy)phenyl]-4-methyl-2-[4-(phenylmethyl)morpholin-2-yl]pentan-2-ol

1-[2-(2-ethoxy-phenyl)-1-phenyl-ethyl]-piperazine

Refernces