1-(Diazomethyl)-4-(trifluoromethyl)benzene

Base Information

Chemical Name:1-(Diazomethyl)-4-(trifluoromethyl)benzene
CAS No.:73900-17-1
Molecular Formula:C8H5F3N2
Molecular Weight:186.136
Hs Code.:
DSSTox Substance ID:DTXSID40503388
Nikkaji Number:J1.058.960F
Wikidata:Q82357160

Synonyms:1-(Diazomethyl)-4-(trifluoromethyl)benzene;73900-17-1;DTXSID40503388;PCSHXURKDDJSFU-UHFFFAOYSA-N

Suppliers and Price of 1-(Diazomethyl)-4-(trifluoromethyl)benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(Diazomethyl)-4-(trifluoromethyl)benzene

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:186.04048265
Heavy Atom Count:13
Complexity:210

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C=[N+]=[N-])C(F)(F)F

Technology Process of 1-(Diazomethyl)-4-(trifluoromethyl)benzene

There total 4 articles about 1-(Diazomethyl)-4-(trifluoromethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 4-methyl-N′-(4-(trifluoromethyl)benzylidene)-benzenesulfonohydrazide

: 73900-17-1
1-(diazomethyl)-4-(trifluoromethyl)benzene

Guidance literature:: With sodium; ethylene glycol; In hexane; at 80 - 90 ℃;
DOI:10.1021/ja00525a025

Reference yield:

: 189096-91-1
{[4-(trifluoromethyl)phenyl]methylidene}hydrazine

: 73900-17-1
1-(diazomethyl)-4-(trifluoromethyl)benzene

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In diethyl ether; dichloromethane; at -78 ℃; for 0.75h; Inert atmosphere;
DOI:10.1021/ol200402m

Reference yield:

: 455-19-6
4-Trifluoromethylbenzaldehyde

: 73900-17-1
1-(diazomethyl)-4-(trifluoromethyl)benzene

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / 12 h / 90 °C / Inert atmosphere; Neat (no solvent)

2: oxalyl dichloride; dimethyl sulfoxide; triethylamine / diethyl ether; dichloromethane / 0.75 h / -78 °C / Inert atmosphere

With oxalyl dichloride; hydrazine hydrate; dimethyl sulfoxide; triethylamine; In diethyl ether; dichloromethane;
DOI:10.1021/ol200402m