(r)-4-Phenyl-3-butyn-2-ol

Base Information

Chemical Name:(r)-4-Phenyl-3-butyn-2-ol
CAS No.:73922-81-3
Molecular Formula:C₁₀H₁₀O
Molecular Weight:146.189
Hs Code.:
DSSTox Substance ID:DTXSID60415974
Nikkaji Number:J464.440I
Wikidata:Q82225070

Synonyms:(r)-4-phenyl-3-butyn-2-ol;73922-81-3;AC1NT5XK;SCHEMBL1657799;DTXSID60415974;(2R)-4-Phenyl-3-butyn-2-ol

Suppliers and Price of (r)-4-Phenyl-3-butyn-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (r)-4-Phenyl-3-butyn-2-ol

Chemical Property:

PSA：20.23000
LogP:1.41890
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:146.073164938
Heavy Atom Count:11
Complexity:166

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C#CC1=CC=CC=C1)O
Isomeric SMILES:C[C@H](C#CC1=CC=CC=C1)O

Technology Process of (r)-4-Phenyl-3-butyn-2-ol

There total 48 articles about (r)-4-Phenyl-3-butyn-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 75-07-0,9002-91-9
acetaldehyde

: 536-74-3
phenylacetylene

: 73922-81-3,81555-86-4,104597-03-7,5876-76-6
4-phenyl-but-3-yn-2-ol

Guidance literature:: With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; at -78 - 20 ℃; for 2h;
DOI:10.1055/s-0030-1260024

Reference yield: 97.0%

: 591-50-4
iodobenzene

: 2028-63-9
but-3-yn-2-ol

: 73922-81-3,81555-86-4,104597-03-7,5876-76-6
4-phenyl-but-3-yn-2-ol

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine; at 20 ℃; for 5h; Inert atmosphere;
DOI:10.1021/ol202176g

Reference yield: 96.0%

: 108-86-1,52753-63-6
bromobenzene

: 2028-63-9
but-3-yn-2-ol

: 73922-81-3,81555-86-4,104597-03-7,5876-76-6
4-phenyl-but-3-yn-2-ol

Guidance literature:: With potassium phosphate; Au₁₃⁽³⁺⁾*6C₁₈H₁₅P*2Cu⁽²⁺⁾*NO₃^(1-)*6C₈H₉S^(1-); In tetrahydrofuran; at 20 ℃; for 8h; Reagent/catalyst; Catalytic behavior; Inert atmosphere;
DOI:10.1016/j.jcat.2021.07.023