1,2,5-Tribromo-3-methoxybenzene

Base Information

Chemical Name:1,2,5-Tribromo-3-methoxybenzene
CAS No.:73931-44-9
Molecular Formula:C7H5Br3O
Molecular Weight:344.82600
Hs Code.:
DSSTox Substance ID:DTXSID70539372
Nikkaji Number:J2.549.410E
Wikidata:Q82415100

Synonyms:1,2,5-Tribromo-3-methoxybenzene;2,3,5-tribromoanisole;73931-44-9;DTXSID70539372

Suppliers and Price of 1,2,5-Tribromo-3-methoxybenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
2,3,5-Tribromoanisole
1g
$ 1564.50

Alichem
2,3,5-Tribromoanisole
500mg
$ 839.45

Alichem
2,3,5-Tribromoanisole
250mg
$ 494.40

Total 0 raw suppliers

Chemical Property of 1,2,5-Tribromo-3-methoxybenzene

Chemical Property:

Melting Point:82°C
Refractive Index:1.5580 (estimate)
Boiling Point:308.5°C (rough estimate)
PSA：9.23000
Density:2.2119 (rough estimate)
LogP:3.98270
XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:343.78700
Heavy Atom Count:11
Complexity:131

Purity/Quality:: 2,3,5-Tribromoanisole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=CC(=C1)Br)Br)Br

Technology Process of 1,2,5-Tribromo-3-methoxybenzene

There total 5 articles about 1,2,5-Tribromo-3-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3,5-dibromo-2-(trimethylsilyl)anisole

: 73931-44-9
2,3,5-tribromoanisole

Guidance literature:: With bromine; In chloroform; at 0 ℃;
DOI:10.1016/j.tetlet.2005.04.065

Reference yield:

: 74137-36-3
3,5-dibromoanisole

: 73931-44-9
2,3,5-tribromoanisole

Guidance literature:: Multi-step reaction with 2 steps

1: LDA / tetrahydrofuran / 0.5 h / -70 °C

2: 3.1 g / Br₂ / CHCl₃ / 0 °C

With bromine; lithium diisopropyl amide; In tetrahydrofuran; chloroform;
DOI:10.1016/j.tetlet.2005.04.065

Reference yield:

: 104-94-9
4-methoxy-aniline

: 73931-44-9
2,3,5-tribromoanisole

Guidance literature:: Multi-step reaction with 2 steps

1: 39 percent / Br₂ / acetic acid

2: 1.) aq. H₂SO₄, NaNO₂, 2.) alcohol; / 1.) 0 deg C, 2.) 0 deg C, 15 min, 3.) heating to 80 deg C, 1 h;

With ethanol; sulfuric acid; bromine; sodium nitrite; In acetic acid;