(R)-pyrrolidine-2-carbonitrile

Base Information

Chemical Name:(R)-pyrrolidine-2-carbonitrile
CAS No.:739363-75-8
Molecular Formula:C5H8N2
Molecular Weight:96.1319
Hs Code.:2933998090
DSSTox Substance ID:DTXSID00375205
Wikidata:Q76148876
Mol file:739363-75-8.mol

Synonyms:(R)-pyrrolidine-2-carbonitrile;739363-75-8;(2R)-pyrrolidine-2-carbonitrile;(2R)-2-PYRROLIDINECARBONITRILE;DTXSID00375205;MFCD12911834;EN300-5266677;A865994

Suppliers and Price of (R)-pyrrolidine-2-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-2-Cyanopyrrolidine
500mg
$ 310.00

Crysdot
(R)-Pyrrolidine-2-carbonitrile 97%
1g
$ 350.00

Chemenu
(2R)-pyrrolidine-2-carbonitriletrifluoroacetate 97%
5g
$ 495.00

Chemenu
(2R)-pyrrolidine-2-carbonitriletrifluoroacetate 97%
25g
$ 1650.00

Chemenu
(2R)-pyrrolidine-2-carbonitriletrifluoroacetate 97%
10g
$ 880.00

American Custom Chemicals Corporation
(R)-PYRROLIDINE-2-CARBONITRILE 95.00%
250MG
$ 216.30

Alichem
(R)-Pyrrolidine-2-carbonitrile
1g
$ 243.00

Alichem
(R)-Pyrrolidine-2-carbonitrile
5g
$ 734.40

ACHEMBLOCK
(2R)-Pyrrolidine-2-carbonitriletrifluoroacetate 97%
1G
$ 350.00

AccelPharmtech
(2R)-2-Pyrrolidinecarbonitrile 97.00%
25G
$ 7320.00

Total 18 raw suppliers

Chemical Property of (R)-pyrrolidine-2-carbonitrile

Chemical Property:

Boiling Point:208.9±33.0 °C(Predicted)
PKA:7.06±0.10(Predicted)
Density:1.01±0.1 g/cm3(Predicted)
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:96.068748264
Heavy Atom Count:7
Complexity:99.9

Purity/Quality:

97% ^*data from raw suppliers

(R)-2-Cyanopyrrolidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(NC1)C#N
Isomeric SMILES:C1C[C@@H](NC1)C#N

Technology Process of (R)-pyrrolidine-2-carbonitrile

There total 6 articles about (R)-pyrrolidine-2-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.6%

: 7677-24-9
trimethylsilyl cyanide

: C₁₃H₁₂N₂O₄

: 739363-75-8
C₅H₈N₂

: 204387-53-1
(2S)-pyrrolidine-2-carbonitrile

Guidance literature:: With silver(I) bromide; tris(2-phenylpyridine)ruthenium; In N,N-dimethyl-formamide; at 90 ℃; Temperature; Inert atmosphere;

Reference yield:

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 739363-75-8
C₅H₈N₂

: 204387-53-1
(2S)-pyrrolidine-2-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: dicyclohexyl-carbodiimide; dmap / dichloromethane / 15 h / 5 °C / Inert atmosphere

2: tris(2-phenylpyridine)ruthenium; silver(I) bromide / N,N-dimethyl-formamide / 90 °C / Inert atmosphere

With dmap; silver(I) bromide; tris(2-phenylpyridine)ruthenium; dicyclohexyl-carbodiimide; In dichloromethane; N,N-dimethyl-formamide;