Benzenesulfonamide, N-(1-methyl-1H-indol-5-yl)-

Base Information

Chemical Name:Benzenesulfonamide, N-(1-methyl-1H-indol-5-yl)-
CAS No.:741708-82-7
Molecular Formula:C15H14N2O2S
Molecular Weight:286.354
Hs Code.:
DSSTox Substance ID:DTXSID00467013
Wikidata:Q82293755

Synonyms:741708-82-7;N-(1-Methyl-1H-indol-5-yl)benzenesulfonamide;Benzenesulfonamide, N-(1-methyl-1H-indol-5-yl)-;DTXSID00467013

Suppliers and Price of Benzenesulfonamide, N-(1-methyl-1H-indol-5-yl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Benzenesulfonamide, N-(1-methyl-1H-indol-5-yl)-

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:286.07759887
Heavy Atom Count:20
Complexity:426

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C=CC2=C1C=CC(=C2)NS(=O)(=O)C3=CC=CC=C3

Technology Process of Benzenesulfonamide, N-(1-methyl-1H-indol-5-yl)-

There total 3 articles about Benzenesulfonamide, N-(1-methyl-1H-indol-5-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 102308-97-4
1-methyl-1H-indol-5-amine

: 98-09-9
benzenesulfonyl chloride

: 741708-82-7
N-(1-methyl-1H-indol-5-yl)benzenesulfonamide

Guidance literature:: With dmap; In pyridine; at 0 - 20 ℃;
DOI:10.1021/ol0490072

Reference yield:

: 6146-52-7
5-nitroindole

: 741708-82-7
N-(1-methyl-1H-indol-5-yl)benzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaH / dimethylformamide / 0 °C

1.2: 92 percent / dimethylformamide / 0 - 20 °C

2.1: H₂ / Raney Ni / ethanol / 2068.59 Torr

3.1: 552 mg / pyridine; DMAP

With pyridine; dmap; hydrogen; sodium hydride; nickel; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/ja043273t

Reference yield:

: 29906-67-0
1-methyl-5-nitro-1H-indole

: 741708-82-7
N-(1-methyl-1H-indol-5-yl)benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Raney Ni / ethanol / 2068.59 Torr

2: 552 mg / pyridine; DMAP

With pyridine; dmap; hydrogen; nickel; In ethanol;
DOI:10.1021/ja043273t