Lithium, [2,4,6-tris(1-methylethyl)phenyl]-

Base Information

• Chemical Name: Lithium, [2,4,6-tris(1-methylethyl)phenyl]-
• CAS No.: 74226-59-8
• Molecular Formula: C15H23Li
• Molecular Weight: 210.289
• DSSTox Substance ID: DTXSID60448429
• Mol file: 74226-59-8.mol

Synonyms:2,4,6-triisopropylphenyllithium;Lithium, [2,4,6-tris(1-methylethyl)phenyl]-;74226-59-8;DTXSID60448429;XZHUOYDDSXMALF-UHFFFAOYSA-N

Chemical Property of Lithium, [2,4,6-tris(1-methylethyl)phenyl]-

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 210.19597917
• Heavy Atom Count: 16
• Complexity: 287

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: [Li+].CC(C)C1=CC(=[C-]C(=C1)C(C)C)C(C)C

Technology Process of Lithium, [2,4,6-tris(1-methylethyl)phenyl]-

There total 1 articles about Lithium, [2,4,6-tris(1-methylethyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4,6-triisopropyl-1-bromobenzene (21524-34-5) → 2,4,6-triisopropylphenyl lithium (74226-59-8)

Guidance literature:

With n-butyllithium; In diethyl ether; hexane; at 20 ℃; for 4h;

DOI:10.1021/ol015927y

Reference yield: 90.0%

2,4,6-triisopropylphenyl lithium (74226-59-8) + Trifluorosupersilylsilan (284664-00-2) → 1,1,1-tri-tert-butyl-2,2-difluoro-2-(2,4,6-triisopropyl-phenyl)-disilane (889360-93-4)

Guidance literature:

In diethyl ether; at -78 - 20 ℃;

DOI:10.1002/anie.200504145

Reference yield: 77.0%

{2,4,6-tris[bis(trimethylsilyl)methyl]phenyl}silane (162608-99-3) + 2,4,6-triisopropylphenyl lithium (74226-59-8) → (2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)(2,4,6-triisopropylphenyl)silane (215877-73-9)

Guidance literature:

In tetrahydrofuran; at -78 ℃; for 10h;

DOI:10.1021/ja980783c

upstream raw materials:

2,4,6-triisopropyl-1-bromobenzene

Downstream raw materials:

ethyl 4-(2',4',6'-triisopropylphenylselanyl)benzoate

chlorobis(2,4,6-triisopropylphenyl)silane

(2,4,6-tris[bis(trimethylsilyl)methyl]phenyl)(2,4,6-triisopropylphenyl)silane

dichloro(2,4,6-tri-isopropylphenyl)phosphane