3-methyl-2-(p-tolyl)quinazolin-4(3H)-one

Base Information

Chemical Name:3-methyl-2-(p-tolyl)quinazolin-4(3H)-one
CAS No.:74375-16-9
Molecular Formula:C16H14N2O
Molecular Weight:250.3
Hs Code.:
DSSTox Substance ID:DTXSID50504841
Wikidata:Q82359604

Synonyms:3-methyl-2-(p-tolyl)quinazolin-4(3H)-one;74375-16-9;3-methyl-2-(4-methylphenyl)-3,4-dihydroquinazolin-4-one;SCHEMBL8503249;DTXSID50504841;3-Methyl-2-(4-methylphenyl)quinazolin-4(3H)-one

Suppliers and Price of 3-methyl-2-(p-tolyl)quinazolin-4(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-methyl-2-(p-tolyl)quinazolin-4(3H)-one

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:250.110613074
Heavy Atom Count:19
Complexity:382

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NC3=CC=CC=C3C(=O)N2C

Technology Process of 3-methyl-2-(p-tolyl)quinazolin-4(3H)-one

There total 24 articles about 3-methyl-2-(p-tolyl)quinazolin-4(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 119072-55-8,7188-38-7
tert-butylisonitrile

: 5720-05-8
4-methylphenylboronic acid

: 4141-08-6
2-Amino-N-methylbenzamid

: 74375-16-9
3-methyl-2-(4-methylphenyl)-4(3H)-quinazolinone

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper diacetate; In N,N-dimethyl-formamide; at 100 ℃; for 8h; Sealed tube; Inert atmosphere;
DOI:10.1021/acs.joc.8b01218

Reference yield: 93.0%

: 104-87-0
4-methyl-benzaldehyde

: 4141-08-6
2-Amino-N-methylbenzamid

: 74375-16-9
3-methyl-2-(4-methylphenyl)-4(3H)-quinazolinone

Guidance literature:: With iodine; In ethanol; Reflux; Green chemistry;
DOI:10.1039/c5ra11262a

Reference yield: 90.0%

: 106-42-3
para-xylene

: 4141-08-6
2-Amino-N-methylbenzamid

: 74375-16-9
3-methyl-2-(4-methylphenyl)-4(3H)-quinazolinone

Guidance literature:: With di-tert-butyl peroxide; iron(III) chloride hexahydrate; In dimethyl sulfoxide; at 110 ℃; for 40h; Sealed tube;
DOI:10.1039/d0ob00866d