1-(2-Hydroxyethyl)-3-(1-phenylethyl)thiourea

Base Information

Chemical Name:1-(2-Hydroxyethyl)-3-(1-phenylethyl)thiourea
CAS No.:74548-41-7
Molecular Formula:C11H16N2OS
Molecular Weight:224.327
Hs Code.:
DSSTox Substance ID:DTXSID70402774

Synonyms:1-(2-hydroxyethyl)-3-(1-phenylethyl)thiourea;74548-41-7;DTXSID70402774;STL181442;AKOS003270835

Suppliers and Price of 1-(2-Hydroxyethyl)-3-(1-phenylethyl)thiourea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(2-Hydroxyethyl)-3-(1-phenylethyl)thiourea

Chemical Property:

Melting Point:94-96 °C(Solv: ethyl acetate (141-78-6))
Boiling Point:361.9±52.0 °C(Predicted)
PSA：83.42000
Density:1.164±0.06 g/cm3(Predicted)
LogP:2.00620
XLogP3:1.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:224.09833431
Heavy Atom Count:15
Complexity:193

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C1=CC=CC=C1)NC(=S)NCCO

Technology Process of 1-(2-Hydroxyethyl)-3-(1-phenylethyl)thiourea

There total 3 articles about 1-(2-Hydroxyethyl)-3-(1-phenylethyl)thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 24277-44-9,32393-32-1,24277-43-8,4478-92-6
(1-isothiocyanato-ethyl)-benzene

: 141-43-5
ethanolamine

: 74548-41-7
3-(2-hydroxyethyl)-1-(1-phenylethyl)thiourea

Guidance literature:: In tetrahydrofuran; at 20 ℃; for 15h; Inert atmosphere;
DOI:10.1016/j.molstruc.2012.12.031

Reference yield:

: 618-36-0
rac-methylbenzylamine

: 74548-41-7
3-(2-hydroxyethyl)-1-(1-phenylethyl)thiourea

Guidance literature:: Multi-step reaction with 2 steps

1: dicyclohexyl-carbodiimide / dichloromethane / 18 h / -10 - 20 °C / Inert atmosphere

2: tetrahydrofuran / 15 h / 20 °C / Inert atmosphere

With dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.molstruc.2012.12.031