2-Methoxyquinolin-8-ol

Base Information

Chemical Name:2-Methoxyquinolin-8-ol
CAS No.:74668-72-7
Molecular Formula:C10H9NO2
Molecular Weight:175.187
Hs Code.:2933499090
DSSTox Substance ID:DTXSID00354055
Wikidata:Q82131987
Mol file:74668-72-7.mol

Synonyms:2-methoxyquinolin-8-ol;74668-72-7;2-methoxy-8-quinolinol;8-quinolinol, 2-methoxy-;8-Hydroxy-2-methoxyquinoline;CHEMBRDG-BB 5175101;2-methoxy-quinolin-8-ol;ChemDiv2_000316;Cambridge id 5175101;Oprea1_314569;SCHEMBL1043719;DTXSID00354055;AJWJCDDMGBKWAW-UHFFFAOYSA-N;HMS1369O08;ZCA66872;2-methoxy-8-quinolinol, AldrichCPR;MFCD00168952;STK019374;AKOS001591778;FS-6117;SB68517;CS-0313149;W-6603

Suppliers and Price of 2-Methoxyquinolin-8-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Methoxyquinolin-8-ol
50mg
$ 65.00

Crysdot
2-Methoxyquinolin-8-ol 95+%
5g
$ 1022.00

Crysdot
2-Methoxyquinolin-8-ol 95+%
1g
$ 340.00

Chemenu
2-Methoxyquinolin-8-ol 95%
1g
$ 321.00

Chemenu
2-Methoxyquinolin-8-ol 95%
5g
$ 963.00

ChemBridge Corporation
2-methoxy-8-quinolinol 95%
5 g
$ 795.00

ChemBridge Corporation
2-methoxy-8-quinolinol 95%
250 mg
$ 121.00

American Custom Chemicals Corporation
2-METHOXY-8-QUINOLINOL 95.00%
1G
$ 1049.03

Alichem
8-Hydroxy-2-methoxyquinoline
10g
$ 1230.46

Alichem
8-Hydroxy-2-methoxyquinoline
5g
$ 1017.31

Total 5 raw suppliers

Chemical Property of 2-Methoxyquinolin-8-ol

Chemical Property:

Vapor Pressure:0.00013mmHg at 25°C
Melting Point:50.5 °C(Solv: hexane (110-54-3))
Boiling Point:324.4oC at 760 mmHg
PKA:10.27±0.10(Predicted)
Flash Point:150oC
PSA：42.35000
Density:1.258g/cm3
LogP:1.94900
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:175.063328530
Heavy Atom Count:13
Complexity:174

Purity/Quality:

99% ^*data from raw suppliers

2-Methoxyquinolin-8-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=NC2=C(C=CC=C2O)C=C1

Technology Process of 2-Methoxyquinolin-8-ol

There total 4 articles about 2-Methoxyquinolin-8-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 642477-85-8
8-(benzyloxy)-2-methoxyquinoline

: 74668-72-7
2-methoxy-8-hydroxyquinoline

Guidance literature:: With hydrogen; 10% palladium on activated carbon; In ethanol; for 3.5h; under 1034.32 Torr;

Reference yield:

: 15450-76-7
quinoline-2,8-diol

: 74668-72-7
2-methoxy-8-hydroxyquinoline

Guidance literature:: Multi-step reaction with 4 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene / isopropyl alcohol / 16 h / 80 °C

2: trichlorophosphate / 16 h / 90 °C

3: methanol / 16 h / 70 °C

4: palladium on activated charcoal; hydrogen / ethanol / 16 h / 25 °C

With palladium on activated charcoal; hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene; trichlorophosphate; In methanol; ethanol; isopropyl alcohol;

Reference yield:

: 63404-84-2
8-(benzyloxy)quinolin-2-ol

: 74668-72-7
2-methoxy-8-hydroxyquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: trichlorophosphate / 16 h / 90 °C

2: methanol / 16 h / 70 °C

3: palladium on activated charcoal; hydrogen / ethanol / 16 h / 25 °C

With palladium on activated charcoal; hydrogen; trichlorophosphate; In methanol; ethanol;