5-methoxy-3-(2-methoxyphenyl)isobenzofuran-1(3H)-one

Base Information

Chemical Name:5-methoxy-3-(2-methoxyphenyl)isobenzofuran-1(3H)-one
CAS No.:748164-68-3
Molecular Formula:C16H14O4
Molecular Weight:270.285
Hs Code.:
DSSTox Substance ID:DTXSID80569928

Synonyms:748164-68-3;5-methoxy-3-(2-methoxyphenyl)isobenzofuran-1(3H)-one;DTXSID80569928;5-Methoxy-3-(2-methoxyphenyl)-2-benzofuran-1(3H)-one

Suppliers and Price of 5-methoxy-3-(2-methoxyphenyl)isobenzofuran-1(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-methoxy-3-(2-methoxyphenyl)isobenzofuran-1(3H)-one

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:270.08920892
Heavy Atom Count:20
Complexity:356

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C(=O)OC2C3=CC=CC=C3OC

Technology Process of 5-methoxy-3-(2-methoxyphenyl)isobenzofuran-1(3H)-one

There total 2 articles about 5-methoxy-3-(2-methoxyphenyl)isobenzofuran-1(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 135-02-4
ortho-anisaldehyde

: 7465-88-5
4-methoxy-N-phenylbenzamide

: 748164-68-3
3-(2'-methoxyphenyl)-5-methoxy-1-isobenzofuranone

Guidance literature:: With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; hexane; 1.) -78 deg C to -20 deg C, 2 h, 2.) room temperature, overnight;
DOI:10.1021/jo00125a054

Reference yield:

: C₂₂H₂₁NO₄

: 748164-68-3
3-(2'-methoxyphenyl)-5-methoxy-1-isobenzofuranone

Guidance literature:: With hydrogenchloride; In water;
DOI:10.3184/030823409X416956

Reference yield: 85.0%

: 110362-30-6
1-<(trimethylsilyl)oxy>-1-methoxy-1,3-butadiene

: 748164-68-3
3-(2'-methoxyphenyl)-5-methoxy-1-isobenzofuranone

: (E)-5-(2-carboxy-5-methoxyphenyl)-5-(2-methoxyphenyl)pent-2-enoic acid

Guidance literature:: 1-<(trimethylsilyl)oxy>-1-methoxy-1,3-butadiene; 3-(2'-methoxyphenyl)-5-methoxy-1-isobenzofuranone; With titanium tetrachloride; In dichloromethane; at 0 ℃;

With potassium hydrogensulfate; In dichloromethane; for 1h;

With sodium hydroxide;
DOI:10.1007/s00706-003-0076-3