1-Phenyl-3-(pyridin-2-ylmethyl)thiourea

Base Information

Chemical Name:1-Phenyl-3-(pyridin-2-ylmethyl)thiourea
CAS No.:75160-54-2
Molecular Formula:C13H13N3S
Molecular Weight:243.332
Hs Code.:
DSSTox Substance ID:DTXSID00353225
Nikkaji Number:J989.370I
Wikidata:Q82130699
ChEMBL ID:CHEMBL1594466

Synonyms:1-phenyl-3-(pyridin-2-ylmethyl)thiourea;75160-54-2;Thiourea, N-phenyl-N'-(2-pyridinylmethyl)-;1-phenyl-3-[(pyridin-2-yl)methyl]thiourea;SBB042385;Maybridge1_001167;Oprea1_661455;MLS000702395;N-2-picolyl-N'-phenylthiourea;CHEMBL1594466;SCHEMBL11190896;HMS544N01;DTXSID00353225;SOUKKKCMEOLENT-UHFFFAOYSA-N;HMS2602D21;STK130900;AKOS000270730;N-Phenyl-N'-2-pyridinylmethylthiourea;N-phenyl-N'-(2-pyridinylmethyl)thiourea;SMR000226194;CS-0358231;Z45804724

Suppliers and Price of 1-Phenyl-3-(pyridin-2-ylmethyl)thiourea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-Phenyl-3-(pyridin-2-ylmethyl)thiourea

Chemical Property:

PSA：76.08000
LogP:3.05250
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:243.08301860
Heavy Atom Count:17
Complexity:239

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC(=S)NCC2=CC=CC=N2

Technology Process of 1-Phenyl-3-(pyridin-2-ylmethyl)thiourea

There total 1 articles about 1-Phenyl-3-(pyridin-2-ylmethyl)thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 3731-51-9
2-(Aminomethyl)pyridine

: 103-72-0
phenyl isothiocyanate

: 75160-54-2
N-phenyl-N'-(pyridin-2-ylmethyl)thiourea

Guidance literature:: With isatoic anhydride resin; In dichloromethane; Ambient temperature; 1.) 14 h; 2.) 90 min;
DOI:10.1016/S0040-4039(98)01778-X

Reference yield: 92.0%

: triphenylphosphinesilver

: 75160-54-2
N-phenyl-N'-(pyridin-2-ylmethyl)thiourea

: 945734-44-1
[(phenyl-3-(2-methylpyridyl)-2-thioureate)diphenylphosphinesilver(I)] nitrate

Guidance literature:: In acetone; acetonitrile; Ag complex in acetone/CH3CN (1:1 v/v) mixed with small excess of ligand in acetone/CH3CN (1:1 v/v), stirred for 2 h in the dark; pptd., recrystn. in the dark from acetone/CH3CN (1:1 v/v) for a few days, elem. anal.;
DOI:10.1016/j.ica.2007.03.025