2-chloro-N-isoxazolo[5,4-b]pyridin-3-ylacetamide

Base Information

Chemical Name:2-chloro-N-isoxazolo[5,4-b]pyridin-3-ylacetamide
CAS No.:753004-48-7
Molecular Formula:C₈H₆ClN₃O₂
Molecular Weight:211.608
Hs Code.:
DSSTox Substance ID:DTXSID90439981
Wikidata:Q82256109

Synonyms:753004-48-7;2-chloro-N-isoxazolo[5,4-b]pyridin-3-ylacetamide;2-Chloro-N-isoxazolo[5,4-b]pyridin-3-yl-acetamide;2-chloro-N-([1,2]oxazolo[5,4-b]pyridin-3-yl)acetamide;2-chloro-N-{[1,2]oxazolo[5,4-b]pyridin-3-yl}acetamide;DTXSID90439981;AKOS005208449;EN300-239359;2-chloro-N-(isoxazolo[5,4-b]pyridin-3-yl)acetamide;F2135-0792

Suppliers and Price of 2-chloro-N-isoxazolo[5,4-b]pyridin-3-ylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Chloro-N-isoxazolo[5,4-b]pyridin-3-ylacetamide 95+%
5g
$ 2360.00

Matrix Scientific
2-Chloro-N-isoxazolo[5,4-b]pyridin-3-ylacetamide 95+%
2.500g
$ 1565.00

Matrix Scientific
2-Chloro-N-isoxazolo[5,4-b]pyridin-3-ylacetamide 95+%
1g
$ 715.00

Total 2 raw suppliers

Chemical Property of 2-chloro-N-isoxazolo[5,4-b]pyridin-3-ylacetamide

Chemical Property:

PSA：71.25000
LogP:0.82200
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:211.0148541
Heavy Atom Count:14
Complexity:227

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-N-isoxazolo[5,4-b]pyridin-3-ylacetamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC2=C(N=C1)ON=C2NC(=O)CCl

Technology Process of 2-chloro-N-isoxazolo[5,4-b]pyridin-3-ylacetamide

There total 3 articles about 2-chloro-N-isoxazolo[5,4-b]pyridin-3-ylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.93%

: 15018-06-1
chloroacetyl bromide

: 92914-74-4
3-aminoisoxazolo[5,4-b]pyridine

: 753004-48-7
3-(chloroacetylamino)isoxazolo[5,4-b]pyridine

Guidance literature:: With potassium carbonate; In tetrahydrofuran; Heating;

Reference yield:

: 6602-54-6
2-chloro-3-pyridinecarbonitrile

: 753004-48-7
3-(chloroacetylamino)isoxazolo[5,4-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 89.6 percent / NH₂OH / ethanol / 5 - 20 °C

2: 82.93 percent / K₂CO₃ / tetrahydrofuran / Heating

With hydroxylamine; potassium carbonate; In tetrahydrofuran; ethanol;

Reference yield:

: 468068-58-8
2-chloropyridino-3-amidoxime

: 753004-48-7
3-(chloroacetylamino)isoxazolo[5,4-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / KOH / diethyl ether / 6 h / Heating

2: 82.93 percent / K₂CO₃ / tetrahydrofuran / Heating

With potassium hydroxide; potassium carbonate; In tetrahydrofuran; diethyl ether;