Ethanesulfonic acid fluoride

Base Information

• Chemical Name: Ethanesulfonic acid fluoride
• CAS No.: 754-03-0
• Molecular Formula: C2H5FO2S
• Molecular Weight: 112.125
• Mol file: 754-03-0.mol

Synonyms:Aethansulfonylfluorid;ethanefluorosulfonate;Aethansulfonsaeure-fluorid;Ethanesulfonyl fluoride;ethanesulfonylfluoride;

Chemical Property of Ethanesulfonic acid fluoride

Chemical Property:

• PSA: 42.52000
• Density: 1.264 g/mL at 25 °C
• LogP: 1.38640

Purity/Quality:

99.3% ^*data from raw suppliers

EthanesulfonylFluoride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Sulfonyl fluoride motif can be used as a connector for the assembly of -SO2- linked small molecules with proteins or nucleic acids. This new click chemistry approach through sulfates is a complimentary approach to using amides and phosphate groups as linkers.

Technology Process of Ethanesulfonic acid fluoride

There total 5 articles about Ethanesulfonic acid fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

Butan-1,4-disulfonylamid (23315-99-3) → ethanesulfonyl fluoride (754-03-0) + Nonafluorobutanesulfonyl fluoride (375-72-4) + perfluorobutane-1,4-bis-sulfonyl fluoride (84246-31-1) + butane-1,4-disulfonyl difluoride

Guidance literature:

With hydrogen fluoride; Further byproducts given; current: 4.5 to 5.5 V; 0.3 to 0.6 Adm^-2;

DOI:10.1016/0022-1139(96)03478-1

Reference yield: 4.7%

Propan-1,3-disulfonylamid (13427-51-5) → ethanesulfonyl fluoride (754-03-0) + Trifluoromethanesulfonyl fluoride (335-05-7) + 1,1,2,2,3,3-hexafluoropropane-1,3-disulfonyl difluoride (82727-16-0) + propane-1,3-disulfonyl difluoride (110073-91-1)

Guidance literature:

With hydrogen fluoride; Further byproducts given; current: 4.5 to 5.5 V; 0.3 to 0.6 Adm^-2;

DOI:10.1016/0022-1139(96)03478-1

Reference yield: 4.3%

propane-1-sulfonamide (24243-71-8) → freon-218 (76-19-7) + Hexafluoroethane (76-16-4) + ethanesulfonyl fluoride (754-03-0) + 1-perfluoropropanesulfonyl fluoride (423-40-5)

Guidance literature:

With hydrogen fluoride; Further byproducts given; current: 4.5 to 5.5 V; 0.3 to 0.6 Adm^-2;

DOI:10.1016/0022-1139(96)03478-1

upstream raw materials:

ethene

Ethanesulfonamide

propane-1-sulfonamide

Propan-1,3-disulfonylamid

Downstream raw materials:

α-Methylsulfonyl-aethyliden-triphenylphosphoran

α-Aethylsulfonyl-aethylidentriphenylphosphoran

[(benzylsulfonyl)(methyl)methylene](triphenyl)phosphorane

α-Neopentylsulfonyl-aethylidentriphenylphosphoran