2,2,2-TRIFLUORO-1-P-TOLYL-ETHANONEOXIME

Base Information

Chemical Name:2,2,2-TRIFLUORO-1-P-TOLYL-ETHANONEOXIME
CAS No.:75703-25-2
Molecular Formula:C9H8F3NO
Molecular Weight:203.164
Hs Code.:2928000090
Mol file:75703-25-2.mol

Synonyms:2,2,2-Trifluoro-4'-methylacetophenone Oxime;2,2,2-Trifluoro-1-(p-tolyl)ethanone oxime;2,2,2-trifluoro-1-(4-methylphenyl)-1-ethanone oxime;p-Tolyl Trifluoromethyl Ketoxime;4-Methyl-a,a,a-trifluoroacetophenone Oxime;2,2,2-TRICHLORO-3'-TRIFLUOROMETHYLACETANILIDE---WHITE CRYSTALLINE;

Suppliers and Price of 2,2,2-TRIFLUORO-1-P-TOLYL-ETHANONEOXIME

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,2,2-Trifluoro-1-(4-methylphenyl)ethanoneOxime
1g
$ 1100.00

Chemenu
2,2,2-Trifluoro-1-(p-tolyl)ethanoneoxime 95%
5g
$ 805.00

American Custom Chemicals Corporation
2,2,2-TRIFLUORO-1-PARA-TOLYL-ETHANONEOXIME 95.00%
5MG
$ 498.15

Alichem
2,2,2-Trifluoro-1-(p-tolyl)ethanoneoxime
5g
$ 699.93

Total 14 raw suppliers

Chemical Property of 2,2,2-TRIFLUORO-1-P-TOLYL-ETHANONEOXIME

Chemical Property:

Vapor Pressure:0.098mmHg at 25°C
Boiling Point:213.286oC at 760 mmHg
PKA:9.48±0.11(Predicted)
Flash Point:82.793oC
PSA：32.59000
Density:1.238g/cm3
LogP:2.73560
Solubility.:Chloroform, Dichloromethane, Ethyl Acetate

Purity/Quality:

97% ^*data from raw suppliers

2,2,2-Trifluoro-1-(4-methylphenyl)ethanoneOxime ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2,2,2-Trifluoro-1-(4-methylphenyl)ethanone Oxime (cas# 75703-25-2) is a compound useful in organic synthesis.

Technology Process of 2,2,2-TRIFLUORO-1-P-TOLYL-ETHANONEOXIME

There total 3 articles about 2,2,2-TRIFLUORO-1-P-TOLYL-ETHANONEOXIME which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 394-59-2
2,2,2-trifluoro-1-(p-tolyl)ethanone

: 75703-25-2,92512-68-0
2,2,2-trifluoro-1-(4-methylphenyl)-1-ethanone oxime

Guidance literature:: With sodium hydroxide; hydroxylamine hydrochloride; In ethanol; for 16h; Heating;

Reference yield:

: 106-38-7
para-bromotoluene

: 75703-25-2
2,2,2-trifluoro-1-(4-methylphenyl)-1-ethanone oxime

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-BuLi / diethyl ether; hexane / 2 h / -40 - 0 °C

1.2: 54 percent / diethyl ether; hexane / 3 h / -60 °C

2.1: hydroxylamine hydrochloride; pyridine / 3 h / 70 °C

With pyridine; n-butyllithium; hydroxylamine hydrochloride; In diethyl ether; hexane;
DOI:10.1021/jm020147w

Reference yield:

: 108-88-3,15644-74-3,16713-13-6
toluene

: 75703-25-2
2,2,2-trifluoro-1-(4-methylphenyl)-1-ethanone oxime

Guidance literature:: Multi-step reaction with 2 steps

1.1: dmap / dichloromethane / 0.17 h / 0 °C

1.2: 16 h / 0 - 20 °C

2.1: hydroxylamine hydrochloride; pyridine / ethanol / 4 h / 60 °C

With pyridine; dmap; hydroxylamine hydrochloride; In ethanol; dichloromethane;
DOI:10.1002/anie.201809149