2-Methyl-1-Benzyloxybenzene

Base Information

• Chemical Name: 2-Methyl-1-Benzyloxybenzene
• CAS No.: 19578-70-2
• Molecular Formula: C14H14O
• Molecular Weight: 198.265
• Hs Code.: 2909309090
• NSC Number: 71617
• DSSTox Substance ID: DTXSID40173242
• Nikkaji Number: J381.717B
• Wikidata: Q83043314
• Mol file: 19578-70-2.mol

Synonyms:2-Methyl-1-Benzyloxybenzene;19578-70-2;1-(Benzyloxy)-2-methylbenzene;1-methyl-2-phenylmethoxybenzene;Benzene, methyl(phenylmethoxy)-;o-Tolylbenzyl ether;Benzene, 1-methyl-2-(phenylmethoxy)-;AI3-11680;O-benzylcresol;Tolylbenzylaether;NSC71617;NCIOpen2_000463;SCHEMBL265584;DTXSID40173242;1-(Benzyloxy)-2-methylbenzene #;1-Methyl-2-(phenylmethoxy)benzene;NSC 71617;NSC-71617;AKOS008913158;AS-59225;FT-0688517;D95792;A880119

Chemical Property of 2-Methyl-1-Benzyloxybenzene

Chemical Property:

• Vapor Pressure: 0.00186mmHg at 25°C
• Boiling Point: 301.7°Cat760mmHg
• Flash Point: 117.4°C
• PSA: 9.23000
• Density: 1.041g/cm³
• LogP: 3.57400
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 198.104465066
• Heavy Atom Count: 15
• Complexity: 172

Purity/Quality:

97% ^*data from raw suppliers

2-Methyl-1-benzyloxybenzene 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CC=C1OCC2=CC=CC=C2

Technology Process of 2-Methyl-1-Benzyloxybenzene

There total 27 articles about 2-Methyl-1-Benzyloxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

ortho-methylphenyl iodide (615-37-2) + benzyl alcohol (100-51-6,185532-71-2) → benzyl 2-methylphenyl ether (19578-70-2)

Guidance literature:

With aluminum oxide; potassium fluoride; copper(l) iodide; 1,10-Phenanthroline; at 110 ℃; for 9h;

DOI:10.1055/s-2005-865198

Reference yield: 97.0%

benzyl chloride (100-44-7) + ortho-cresol (95-48-7,77504-84-8) → benzyl 2-methylphenyl ether (19578-70-2)

Guidance literature:

With sodium hydroxide; tetrabutylammomium bromide; In dichloromethane; water; at 25 ℃; for 4h;

DOI:10.1055/s-1982-29976

Reference yield: 94.0%

2-bromophenyl benzyl ether (31575-75-4) + methyl iodide (74-88-4) → benzyl 2-methylphenyl ether (19578-70-2)

Guidance literature:

2-bromophenyl benzyl ether; With tert.-butyl lithium; In tetrahydrofuran; hexane; pentane; at 25 ℃; Flow reactor;

methyl iodide; In tetrahydrofuran; hexane; pentane; at 25 ℃; for 0.00833333h; Flow reactor;

DOI:10.1039/c7cc08460a

upstream raw materials:

benzyl bromide

sodium o-cresolate

benzyl chloride

potassium o-cresolate

Downstream raw materials:

ortho-cresol

2-benzyl-6-methylphenol

2-methyl-4-benzylphenol

2,4-Dibenzyl-6-methyl-phenol