2-(2,3,4-Trimethoxyphenyl)cyclohexanol

Base Information

• Chemical Name: 2-(2,3,4-Trimethoxyphenyl)cyclohexanol
• CAS No.: 92730-59-1
• Molecular Formula: C₁₅H₂₂O₄
• Molecular Weight: 266.337
• NSC Number: 84520
• DSSTox Substance ID: DTXSID80292668
• Mol file: 92730-59-1.mol

Synonyms:92730-59-1;2-(2,3,4-trimethoxyphenyl)cyclohexanol;NSC84520;DTXSID80292668;NSC-84520

Chemical Property of 2-(2,3,4-Trimethoxyphenyl)cyclohexanol

Chemical Property:

• Vapor Pressure: 2.52E-06mmHg at 25°C
• Boiling Point: 376.1°Cat760mmHg
• Flash Point: 181.3°C
• Density: 1.111g/cm³
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 266.15180918
• Heavy Atom Count: 19
• Complexity: 271

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C(=C(C=C1)C2CCCCC2O)OC)OC

Technology Process of 2-(2,3,4-Trimethoxyphenyl)cyclohexanol

There total 3 articles about 2-(2,3,4-Trimethoxyphenyl)cyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(2,3,4-trimethoxyphenyl)cyclohexanone (101499-35-8) → trans-2-(2,3,4-Trimethoxy-phenyl)-cyclohexanol (92730-59-1)

Guidance literature:

With lithium aluminium tetrahydride;

DOI:10.1021/jo01345a027

Reference yield:

1-cyclohex-1-enyl-2,3,4-trimethoxy-benzene (6773-00-8) → trans-2-(2,3,4-Trimethoxy-phenyl)-cyclohexanol (92730-59-1)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) MCPBA, (ii) H₂SO₄

2: LiAlH₄

With lithium aluminium tetrahydride;

DOI:10.1021/jo01345a027

Reference yield:

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → trans-2-(2,3,4-Trimethoxy-phenyl)-cyclohexanol (92730-59-1)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) Mg, THF, (ii) /BRN= 385735/

2: (i) MCPBA, (ii) H₂SO₄

3: LiAlH₄

With lithium aluminium tetrahydride;

DOI:10.1021/jo01345a027

upstream raw materials:

2-(2,3,4-trimethoxyphenyl)cyclohexanone

1-cyclohex-1-enyl-2,3,4-trimethoxy-benzene

cyclohexanone